From the Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital.
Departments of Urology.
Clin Nucl Med. 2020 Aug;45(8):632-635. doi: 10.1097/RLU.0000000000003099.
A 75-year-old man with a history of prostate cancer (T1N0M0, Gleason score 4 + 3) was referred to radionuclide bone scan and Ga-PSMA PET/CT to detect recurrence. Multiple abnormal foci were observed in the axial and appendicular skeleton, which were suggestive of metastatic superscan from prostate cancer. However, histopathological examinations (from bone biopsy) did not support the metastases from prostate cancer. Ga-FAPI PET/CT was then performed to detect the occult tumor, which showed intense activity in the gastric wall. Subsequent gastroscopy examination revealed the diagnosis of GSRCC (gastric signet-ring cell carcinoma). The diagnosis of GSRCC with widespread bone metastases was finally made.
一位 75 岁男性，有前列腺癌病史（T1N0M0，Gleason 评分 4+3），被转介进行放射性核素骨扫描和 Ga-PSMA PET/CT 以检测复发情况。轴向和附肢骨骼多处异常病灶，提示前列腺癌转移超扫描。然而，组织病理学检查（来自骨活检）不支持前列腺癌转移。随后进行 Ga-FAPI PET/CT 以检测隐匿性肿瘤，结果显示胃壁活性明显增强。随后的胃镜检查诊断为 GSRCC（胃印戒细胞癌）。最终诊断为广泛骨转移的 GSRCC。
