Haq I, Ullah R, Din M, Ahmad S, Anwar F, Ali M, Khan H Ullah
Department of Genetics, Hazara University Mansehra, Pakistan.
Department of Biotechnology, University of Malakand, Pakistan.
New Microbes New Infect. 2020 Apr 23;35:100685. doi: 10.1016/j.nmni.2020.100685. eCollection 2020 May.
Acquired immunodeficiency syndrome (AIDS) is a global epidemic that impacts the lives of many individuals each year. Human immunodeficiency virus (HIV) is a retrovirus that infects human CD4 T helper cells and macrophages thereby causing severe immune disease. The current study aimed to examine the prevalence of HIV among the blood donors of Khyber Pakhtunkhwa at Peshawar. In this study, a total of 8634 volunteers who donated blood were carefully screened for HIV using ELISA and RT-PCR techniques. Among the volunteers ( = 8634), 63 were positive by both ELISA and RT-PCR; which shows a prevalence of 0.73%. Both diagnostic techniques exhibited similar results. All the positive individuals were informed immediately and advised to start treatment to control the progression of the infection. It was concluded that HIV is on the rise in Peshawar, and routine screening and preventive measures are immediately required to address the urgent situation of HIV infection.
获得性免疫缺陷综合征（艾滋病）是一种全球流行病，每年影响着许多人的生活。人类免疫缺陷病毒（HIV）是一种逆转录病毒，它感染人类CD4辅助性T细胞和巨噬细胞，从而导致严重的免疫疾病。当前的研究旨在调查白沙瓦开伯尔-普赫图赫瓦省献血者中HIV的流行情况。在这项研究中，使用酶联免疫吸附测定（ELISA）和逆转录-聚合酶链反应（RT-PCR）技术对总共8634名献血志愿者进行了HIV仔细筛查。在这些志愿者（n = 8634）中，有63人ELISA和RT-PCR检测均呈阳性；这表明流行率为0.73%。两种诊断技术显示出相似的结果。所有阳性个体均立即得到通知，并被建议开始治疗以控制感染的进展。得出的结论是，白沙瓦的HIV感染率正在上升，迫切需要进行常规筛查和采取预防措施来应对HIV感染的紧急情况。
