Center of Innovation in Long-Term Services and Supports Providence VA Medical Center Providence RI.
Primary Care and Population Medicine Program Warren Alpert Medical School of Brown University Providence RI.
J Am Heart Assoc. 2020 Jun 2;9(11):e013989. doi: 10.1161/JAHA.119.013989. Epub 2020 May 27.
Background Palliative care supports quality of life, symptom control, and goal setting in heart failure (HF) patients. Unlike hospice, palliative care does not restrict life-prolonging therapy. This study examined the association between palliative care during hospitalization for HF on the subsequent transitions and procedures. Methods and Results Veterans admitted to hospitals with HF from 2010 to 2015 were randomly selected for the Veterans Administration External Peer Review Program. Variables pertaining to demographic, clinical, laboratory, and usage were captured from Veterans Administration electronic records. Patients receiving hospice services before admission were excluded. Patients who received palliative care were propensity matched to those who did not. The primary outcomes were whether the patient experienced transitions or procedures in the 6 months after admission. Transitions included multiple readmissions (≥2) or intensive care admissions and procedures included mechanical ventilation, pacemaker implantation, or defibrillator implantation. Among 57 182 hospitalized HF patients, 1431 received palliative care, and were well matched to 1431 without (standardized mean differences ≤ ±0.05 on all matched variables). Palliative care was associated with significantly fewer multiple rehospitalizations (30.9% versus 40.3%, <0.001), mechanical ventilation (2.8% versus 5.4%, =0.004), and defibrillator implantation (2.1% versus 3.6%, =0.01). After adjustment for facility fixed effects, palliative care consultation was associated with a significantly reduced hazard of multiple readmissions (adjusted hazard ratio=0.73, 95% CI, 0.64-0.84) and mechanical ventilation (adjusted hazard ratio=0.76, 95% CI, 0.67-0.87). Conclusions Palliative care during HF admissions was associated with fewer readmissions and less mechanical ventilation. When available, engagement of HF patients and caregivers in palliative care for symptom control, quality of life, and goals of care discussions may be associated with reduced rehospitalizations and mechanical ventilation.
姑息治疗支持心力衰竭(HF)患者的生活质量、症状控制和目标设定。与临终关怀不同,姑息治疗并不限制延长生命的治疗。本研究探讨了 HF 住院期间姑息治疗与随后的转归和程序之间的关联。
从 2010 年至 2015 年,退伍军人管理局从因 HF 住院的退伍军人中随机选择参加退伍军人管理局外部同行评审计划。从退伍军人管理局电子记录中获取与人口统计学、临床、实验室和使用相关的变量。排除入院前接受临终关怀服务的患者。将接受姑息治疗的患者与未接受姑息治疗的患者进行倾向评分匹配。主要结局是患者在入院后 6 个月内是否经历转归或程序。转归包括多次再入院(≥2 次)或入住重症监护病房,程序包括机械通气、起搏器植入或除颤器植入。在 57182 例因 HF 住院的患者中,1431 例接受姑息治疗,与 1431 例未接受姑息治疗的患者匹配良好(所有匹配变量的标准化均差≤±0.05)。姑息治疗与多次再入院(30.9%对 40.3%,<0.001)、机械通气(2.8%对 5.4%,=0.004)和除颤器植入(2.1%对 3.6%,=0.01)的发生率显著降低相关。在调整设施固定效应后,姑息治疗咨询与多次再入院(调整后的危险比=0.73,95%CI,0.64-0.84)和机械通气(调整后的危险比=0.76,95%CI,0.67-0.87)的风险显著降低相关。
HF 住院期间姑息治疗与再入院和机械通气减少相关。当姑息治疗可用时,让 HF 患者及其护理人员参与姑息治疗以进行症状控制、生活质量和治疗目标的讨论,可能与减少再入院和机械通气相关。