Department of Chemistry, Kumamoto University, 2-39-1 Kurokami Chuo-ku, Kumamoto, 860-8555, Japan; International Research Organization for Advanced Science and Technology, Kumamoto University, 2-39-1 Kurokami Chuo-ku, Kumamoto, 860-8555, Japan.
Department of Chemistry, Kumamoto University, 2-39-1 Kurokami Chuo-ku, Kumamoto, 860-8555, Japan.
Talanta. 2020 Aug 15;216:120989. doi: 10.1016/j.talanta.2020.120989. Epub 2020 Apr 6.
The sensitivity of an ion chromatography system was improved using electrodialytic post-column enrichment. Even though post-column reactions, such as suppression, have been used to enhance the sensitivity, there are only a few methods available to increase the concentration and improve the sensitivity. Post-column in-line enrichment was achieved with a miniaturized crossflow ion transfer device (ITD) prepared in our laboratory. In the crossflow ITD, separated ionic solutes in the suppressed eluent were transferred into the acceptor solution (in-line purified ultrapure water), which had a flow rate less than that of the eluent. Because of highly efficient ion transfer, the analytes were enriched in the acceptor solution and the enrichment factor was depending on flow rate ratio of acceptor to eluent. Furthermore, the crossflow ITD minimized peak dispersion in the channel. The limit of detection improved by 5.0 ± 0.3 times when the flow rate ratio was 10.
采用电渗析柱后富集技术提高离子色谱系统的灵敏度。尽管柱后反应（如抑制）已被用于提高灵敏度，但可用的方法只有几种，这些方法可以增加浓度并提高灵敏度。通过我们实验室制备的小型化错流离子迁移装置（ITD）实现了柱后在线富集。在错流 ITD 中，被抑制洗脱液中的分离离子溶质被转移到接受溶液（在线纯化超纯水）中，接受溶液的流速小于洗脱液的流速。由于高效的离子迁移，分析物在接受溶液中被富集，并且富集因子取决于接受溶液与洗脱液的流速比。此外，错流 ITD 使通道中的峰展宽最小化。当流速比为 10 时，检测限提高了 5.0±0.3 倍。
