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揭示三楞草脂溶性部位的生物活性:化学成分鉴定及对耐甲氧西林金黄色葡萄球菌的体外抗菌活性。

Unveiling the bioactivity of Allium triquetrum L. lipophilic fractions: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus.

机构信息

Laboratoire de Biomathématiques, Biophysique, Biochimie et Scientométrie, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000 Bejaia, Algérie.

Faculté des Sciences de la Nature et de la Vie, Département des Troncs Communs, Université de Bejaia, 06000 Bejaia, Algérie and Laboratoire de Physico-Chimie des Matériaux et Catalyse, Faculté des Sciences Exactes, Université de Bejaia, 06000 Bejaia, Algérie.

出版信息

Food Funct. 2020 Jun 24;11(6):5257-5265. doi: 10.1039/d0fo00769b.

DOI:10.1039/d0fo00769b
PMID:32458905
Abstract

The lipophilic composition of Allium triquetrum L. bulbs, flowers and leaves was studied for the first time by GC-MS. Sixty compounds were firstly identified in A. triquetrum L. Fatty acids represented the major lipophilic family among the studied extracts, with (9Z,12Z,15Z)-octadeca-9,12,15-trienoic and (9Z,12Z)-octadeca-9,12-dienoic acids being the major constituents of this family. A long chain aliphatic ketone, namely hentriacontan-16-one, was mainly found in flowers and leaves. Flowers and leaves were also found to be rich in long chain aliphatic alkanes and alcohols, respectively. Sterols, monoglycerides, aromatic compounds and long chain aliphatic aldehydes were found in lower amounts. The antibacterial activity of A. triquetrum bulb, flower and leaf extracts against methicillin-resistant Staphylococcus aureus (MRSA) growth was in vitro assessed. Bulb and flower extracts showed significant MRSA growth inhibition. Overall, these valuable findings can contribute to the valorization of A. triquetrum L. as a source of value-added phytochemicals, specifically as antibacterial agents and for nutraceutical applications.

摘要

首次采用 GC-MS 对三楞草鳞茎、花和叶的脂溶性成分进行了研究。首次在三楞草中鉴定了 60 种化合物。在所研究的提取物中,脂肪酸是主要的脂溶性族,其中(9Z,12Z,15Z)-十八碳-9,12,15-三烯酸和(9Z,12Z)-十八碳-9,12-二烯酸是该族的主要成分。一种长链脂肪酮,即三十烷-16-酮,主要存在于花和叶中。花和叶还富含长链脂肪烷烃和醇,分别。甾醇、单甘油酯、芳香族化合物和长链脂肪醛的含量较低。体外评估了三楞草鳞茎、花和叶提取物对耐甲氧西林金黄色葡萄球菌(MRSA)生长的抑菌活性。鳞茎和花提取物对 MRSA 生长有明显的抑制作用。总的来说,这些有价值的发现可以促进三楞草 L. 作为有价值的植物化学物质的来源的增值,特别是作为抗菌剂和营养应用。

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