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去细胞支架在椎间盘再生中的应用。

Decellularized Scaffolds for Intervertebral Disc Regeneration.

机构信息

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal; ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

出版信息

Trends Biotechnol. 2020 Sep;38(9):947-951. doi: 10.1016/j.tibtech.2020.05.002. Epub 2020 May 25.

DOI:10.1016/j.tibtech.2020.05.002
PMID:32466967
Abstract

In the last decade, intervertebral disc (IVD) decellularization has gained significant attention for tissue regenerative purposes as a successful therapeutic alternative for low back pain (LBP). We discuss the recent advances in IVD decellularization, repopulation, and sterilization procedures, highlighting the major challenges that need to be addressed for clinical translation.

摘要

在过去十年中,椎间盘(IVD)去细胞化因其作为治疗腰痛(LBP)的成功治疗替代方案而受到组织再生目的的广泛关注。我们讨论了 IVD 去细胞化、再细胞化和灭菌程序的最新进展,强调了需要解决的主要挑战,以实现临床转化。

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Decellularized Scaffolds for Intervertebral Disc Regeneration.去细胞支架在椎间盘再生中的应用。
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[Regeneration strategies of intervertebral disc].[椎间盘的再生策略]
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