Mousavi-Hasanzadeh Morteza, Sarmadian Hossein, Ghasemikhah Reza, Didehdar Mojtaba, Shahdoust Maryam, Maleki Mahshid, Taheri Mahdieh
1Student Research Committee, Arak University of Medical Sciences, Arak, Iran.
2Department of Infectious Diseases, Arak University of Medical Sciences, Arak, Iran.
Trop Med Health. 2020 May 19;48:35. doi: 10.1186/s41182-020-00222-x. eCollection 2020.
Toxoplasmosis is a parasitic infectious disease, and is the causative factor of this intracellular protozoan disease. Due to the lack of information about the rate of in general papulation of Markazi Province in Iran, the current study was conducted to determine the prevalence of toxoplasmosis and the related risk factor analysis in the general population of Markazi Province.
This cross-sectional study was performed within 6 months on individuals who were referred to diagnostic laboratories in Markazi Province. The demographic and background information of the subjects were collected using a questionnaire. Three milliliters of blood samples was collected from the participants under sterile conditions. The sera were separated and evaluated for levels of anti- IgG antibody using a commercial enzyme-linked immunosorbent assay (ELISA) method. The collected data were analyzed by the SPSS software using descriptive statistics and chi-square test.
Out of 824 people from the general population of Markazi Province who were investigated in this study, 276 (33.5%) had anti- antibodies in their blood. According to the logistic regression model, gender variables, location, marital status, and having a cat at home do not affect the chances of contracting the parasite. Furthermore, the chance of contracting the parasite in 41- to 50-year-olds is 0.85 times the one in the 20- to 30-year-olds. The prevalence of toxoplasmosis in men and women in Markazi Province was 33% and 34.5%, respectively.
The mean prevalence of infection in the age groups of 20-40, and ≥ 40 years was estimated to be 24.7%, and 40.8%, respectively. These rates were significantly lower than the national results (44%, and 55%, respectively). Therefore, regarding to the health authorities, it is necessary to raise the level of awareness of people of the region, especially at-risk groups about the transmittance and prevention methods, and infection risk factors in order to prevent the occurrence of infection and reduce the prevalence and incidence of the disease.
弓形虫病是一种寄生虫感染性疾病，是这种细胞内原生动物疾病的致病因素。由于缺乏关于伊朗马尔卡齐省普通人群中弓形虫感染率的信息，本研究旨在确定马尔卡齐省普通人群中弓形虫病的患病率及相关危险因素分析。
本横断面研究在6个月内对转诊至马尔卡齐省诊断实验室的个体进行。使用问卷收集受试者的人口统计学和背景信息。在无菌条件下从参与者采集3毫升血液样本。分离血清并使用商业酶联免疫吸附测定（ELISA）方法评估抗IgG抗体水平。使用SPSS软件对收集的数据进行描述性统计和卡方检验分析。
在本研究中调查的马尔卡齐省普通人群的824人中（33.5%）血液中有抗弓形虫抗体。根据逻辑回归模型，性别变量、居住地点、婚姻状况和家中养猫不会影响感染寄生虫的几率。此外，41至50岁人群感染寄生虫的几率是20至30岁人群的0.85倍。马尔卡齐省男性和女性的弓形虫病患病率分别为33%和34.5%。
估计20至40岁和≥40岁年龄组的弓形虫感染平均患病率分别为24.7%和40.8%。这些比率显著低于全国结果（分别为44%和55%）。因此，对于卫生当局而言，有必要提高该地区民众，特别是高危人群对传播途径、预防方法和感染危险因素的认识，以预防弓形虫感染的发生并降低该疾病的患病率和发病率。
