Huang Sheng, Sing Swee Leong, de Looze Geoff, Wilson Robert, Yeong Wai Yee
Singapore Centre for 3D Printing, School of Mechanical & Aerospace Engineering, Nanyang Technological University, N3.1-B2C-03, 50 Nanyang Avenue, 639798, Singapore.
Commonwealth Scientific and Industrial Research Organisation, Research Way, Clayton, Vic, 3168, Australia.
J Mech Behav Biomed Mater. 2020 Aug;108:103775. doi: 10.1016/j.jmbbm.2020.103775. Epub 2020 Apr 14.
In this study, laser powder bed fusion (L-PBF), also known as selective laser melting (SLM), was used to fabricate samples of titanium-tantalum (TiTa) alloys with 0, 10, 30 and 50 wt% of tantalum using in-situ alloying. As-fabricated samples comprised of randomly-dispersed pure tantalum particles in a titanium-tantalum matrix. Porosity and unmelted tantalum particles of the samples were revealed using an optical microscope (OM). The microstructure of the alloys were determined by combination of field emission scanning electron microscopy (FE-SEM), electron back scatter diffraction (EBSD) and X-ray diffraction (XRD). The mechanical properties of the alloys were investigated with tensile and Vickers hardness tests. To ascertain the suitability of these alloys as biomaterials, Ti50Ta scaffolds with 60% porosity were characterized biologically. This study further shows that porous TiTa scaffolds fabricated using L-PBF are biocompatible with comparable biological results and manufacturability as Ti6Al4V and commercially pure titanium, based on the results obtained from cell culture with human osteosarcoma cell line SAOS-2.
在本研究中，激光粉末床熔融（L-PBF，也称为选择性激光熔化（SLM））被用于通过原位合金化制备钽含量为0、10、30和50 wt%的钛钽（TiTa）合金样品。制备出的样品由在钛钽基体中随机分散的纯钽颗粒组成。使用光学显微镜（OM）揭示样品的孔隙率和未熔化的钽颗粒。通过场发射扫描电子显微镜（FE-SEM）、电子背散射衍射（EBSD）和X射线衍射（XRD）相结合的方法确定合金的微观结构。通过拉伸试验和维氏硬度测试研究合金的力学性能。为了确定这些合金作为生物材料的适用性，对孔隙率为60%的Ti50Ta支架进行了生物学表征。基于用人骨肉瘤细胞系SAOS-2进行细胞培养所获得的结果，本研究进一步表明，使用L-PBF制备的多孔TiTa支架具有生物相容性，其生物学结果和可制造性与Ti6Al4V及商业纯钛相当。
