Alencar Cristiane deM, Ortiz Mariangela Ig, Silva Fabio A, Alves Eliane B, Araújo Jesuína Ln, Silva Cecy M
School of Dentistry, Federal University of Para, Belem, PA,
School of Dentistry, Federal University of Para, Belem, PA, Brazil.
Am J Dent. 2020 Jun;33(3):138-144.
To evaluate the effect of nanohydroxyapatite ( nHAP) associated with photobiomodulation (PBM) in the control of dentin hypersensitivity (DH). (C-Shape It).
32 subjects with 83 hypersensitive teeth were randomized into four groups (N =8) : GPlacebo - simulated PBM (without light emission) followed by the application of nHAP-free toothpaste; GLaser - PBM followed by the application of nHAP-free toothpaste; GnHAP - simulated PBM followed by the application of nHAP; GLasernHAP - PBM followed by the application of nHAP. A visual analogue scale (VAS) was used to measure DH after a tactile and evaporative stimulus. DH evaluations were performed at four times: baseline, 1st, and 2nd treatment sessions, and 1 month. A questionnaire was used to evaluate the risk factors associated with DH intensity. Mixed-design ANOVA followed by Tukey test and logistic regression were used.
The mechanical stimulus showed a significant reduction in DH in all experimental groups (P< 0.05) at the 2nd treatment session. For the evaporative stimulus, the GLasernHAP group presented a significant reduction in DH at the 1st treatment session (P< 0.05). Intragroup analysis showed that only the GnHAP group showed regression of DH at 1 month for the two applied stimuli. The variables of parafunctional habits, diets rich in acidic drinks and anxiety had significant relationships with the intensity of DH (P< 0.05).
The use of nHAP and application of PBM to laser are effective in the control of dentin hypersensitivity. However, their association did not enhance the desensitizing effect.
评估纳米羟基磷灰石（nHAP）联合光生物调节（PBM）对牙本质过敏（DH）的控制效果。（C形根管）
将32名患有83颗过敏牙齿的受试者随机分为四组（每组n = 8）：G安慰剂组——模拟PBM（无发光），随后使用不含nHAP的牙膏；G激光组——PBM，随后使用不含nHAP的牙膏；GnHAP组——模拟PBM，随后使用nHAP；GLasernHAP组——PBM，随后使用nHAP。采用视觉模拟量表（VAS）在触觉和蒸发刺激后测量DH。在四个时间点进行DH评估：基线、第1次和第2次治疗 session，以及1个月。使用问卷评估与DH强度相关的危险因素。采用混合设计方差分析，随后进行Tukey检验和逻辑回归分析。
在第2次治疗session时，所有实验组的机械刺激均显示DH显著降低（P < 0.05）。对于蒸发刺激，GLasernHAP组在第1次治疗session时DH显著降低（P < 0.05）。组内分析表明，仅GnHAP组在1个月时对于两种应用刺激均显示DH消退。异常功能习惯、富含酸性饮料的饮食和焦虑等变量与DH强度有显著关系（P < 0.05）。
使用nHAP以及对激光应用PBM对控制牙本质过敏有效。然而，它们的联合并未增强脱敏效果。
