• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Insights into the Multi-Dimensional Dynamic Landscape of Epithelial-Mesenchymal Plasticity through Inter-Disciplinary Approaches.通过跨学科方法洞察上皮-间质可塑性的多维动态格局
J Clin Med. 2020 May 27;9(6):1624. doi: 10.3390/jcm9061624.
2
Revisiting epithelial-mesenchymal transition in cancer metastasis: the connection between epithelial plasticity and stemness.重新审视癌症转移中的上皮-间质转化：上皮可塑性与干性之间的联系。
Mol Oncol. 2017 Jul;11(7):792-804. doi: 10.1002/1878-0261.12096. Epub 2017 Jun 26.
3
Quantifying the landscape and kinetic paths for epithelial-mesenchymal transition from a core circuit.从核心回路量化上皮-间质转化的格局和动力学路径。
Phys Chem Chem Phys. 2016 Jul 21;18(27):17949-56. doi: 10.1039/c6cp03174a. Epub 2016 Jun 21.
4
The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states.Z-cad双荧光传感器可检测上皮细胞和间充质细胞状态之间的动态变化。
BMC Biol. 2016 Jun 17;14:47. doi: 10.1186/s12915-016-0269-y.
5
Insights into Biological Role of LncRNAs in Epithelial-Mesenchymal Transition.长链非编码 RNA 在 EMT 中生物学作用的研究进展。
Cells. 2019 Sep 30;8(10):1178. doi: 10.3390/cells8101178.
6
Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis.上皮-间充质可塑性在癌症进展和转移中的作用。
Dev Cell. 2019 May 6;49(3):361-374. doi: 10.1016/j.devcel.2019.04.010.
7
Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer.卵巢癌上皮-间质表型可塑性的复杂决定因素
Cancers (Basel). 2017 Aug 9;9(8):104. doi: 10.3390/cancers9080104.
8
Epithelial-to-mesenchymal plasticity of cancer stem cells: therapeutic targets in hepatocellular carcinoma.癌症干细胞的上皮-间质可塑性：肝细胞癌的治疗靶点
J Hematol Oncol. 2016 Aug 30;9(1):74. doi: 10.1186/s13045-016-0307-9.
9
Epithelial-mesenchymal transition in pancreatic cancer: Is it a clinically significant factor?胰腺癌中的上皮-间质转化：它是一个具有临床意义的因素吗？
Biochim Biophys Acta. 2015 Jan;1855(1):43-9. doi: 10.1016/j.bbcan.2014.11.004. Epub 2014 Nov 26.
10
Breast cancer cells: Focus on the consequences of epithelial-to-mesenchymal transition.乳腺癌细胞：关注上皮-间质转化的后果。
Int J Biochem Cell Biol. 2017 Jun;87:23-26. doi: 10.1016/j.biocel.2017.03.014. Epub 2017 Mar 20.

引用本文的文献

1
A novel anti-lung cancer agent inhibits proliferation and epithelial-mesenchymal transition.一种新型的抗癌药物可抑制增殖和上皮-间充质转化。
J Int Med Res. 2022 Apr;50(4):3000605211066300. doi: 10.1177/03000605211066300.

本文引用的文献

1
Epithelial-Mesenchymal Transition-Related MicroRNAs and Their Target Genes in Colorectal Cancerogenesis.结直肠癌发生过程中上皮-间质转化相关的微小RNA及其靶基因
J Clin Med. 2019 Oct 3;8(10):1603. doi: 10.3390/jcm8101603.
2
Iduronate-2-Sulfatase-Regulated Dermatan Sulfate Levels Potentiate the Invasion of Breast Cancer Epithelia through Collagen Matrix.艾杜糖醛酸-2-硫酸酯酶调节的硫酸皮肤素水平增强乳腺癌上皮细胞通过胶原基质的侵袭能力。
J Clin Med. 2019 Sep 30;8(10):1562. doi: 10.3390/jcm8101562.
3
Dynamics of Phenotypic Heterogeneity Associated with EMT and Stemness during Cancer Progression.癌症进展过程中与上皮-间质转化和干性相关的表型异质性动态变化
J Clin Med. 2019 Sep 25;8(10):1542. doi: 10.3390/jcm8101542.
4
A Novel Ex Vivo System Using 3D Polymer Scaffold to Culture Circulating Tumor Cells from Breast Cancer Patients Exhibits Dynamic E-M Phenotypes.一种使用3D聚合物支架培养乳腺癌患者循环肿瘤细胞的新型体外系统展现出动态的上皮-间质表型。
J Clin Med. 2019 Sep 16;8(9):1473. doi: 10.3390/jcm8091473.
5
Multi-Omics Characterization of the Spontaneous Mesenchymal-Epithelial Transition in the PMC42 Breast Cancer Cell Lines.PMC42乳腺癌细胞系中自发间充质-上皮转化的多组学特征分析
J Clin Med. 2019 Aug 19;8(8):1253. doi: 10.3390/jcm8081253.
6
Deciphering Hydrodynamic and Drug-Resistant Behaviors of Metastatic EMT Breast Cancer Cells Moving in a Constricted Microcapillary.解析转移性上皮-间质转化乳腺癌细胞在狭窄微毛细管中迁移的流体动力学和耐药行为
J Clin Med. 2019 Aug 9;8(8):1194. doi: 10.3390/jcm8081194.
7
ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients.ATP合酶亚基ε过表达通过调节AMPK信号通路诱导上皮-间质转化促进转移，是结直肠癌患者预后不良的标志物。
J Clin Med. 2019 Jul 21;8(7):1070. doi: 10.3390/jcm8071070.
8
Metabolic Plasticity and Epithelial-Mesenchymal Transition.代谢可塑性与上皮-间质转化
J Clin Med. 2019 Jul 3;8(7):967. doi: 10.3390/jcm8070967.
9
Morphological State Transition Dynamics in EGF-Induced Epithelial to Mesenchymal Transition.表皮生长因子诱导上皮-间质转化中的形态学状态转变动力学
J Clin Med. 2019 Jun 26;8(7):911. doi: 10.3390/jcm8070911.
10
Interrogation of Phenotypic Plasticity between Epithelial and Mesenchymal States in Breast Cancer.乳腺癌上皮和间充质状态之间的表型可塑性研究
J Clin Med. 2019 Jun 21;8(6):893. doi: 10.3390/jcm8060893.

通过跨学科方法洞察上皮-间质可塑性的多维动态格局

Insights into the Multi-Dimensional Dynamic Landscape of Epithelial-Mesenchymal Plasticity through Inter-Disciplinary Approaches.

作者信息

Kumar Jolly Mohit, Celia-Terrassa Toni

机构信息

Centre for BioSystems Science and Engineering, Indian Institute of Science, Bangalore 560012, India.

Cancer Research Program, IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.

出版信息

J Clin Med. 2020 May 27;9(6):1624. doi: 10.3390/jcm9061624.

DOI:10.3390/jcm9061624
PMID:32471235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7356048/
Abstract

Epithelial-mesenchymal transition (EMT), first described by Dr. Elizabeth (Betty) Hay in the 1980s during vertebrate embryonic development [1], has important implications in cancer aggressiveness [2]. [...].

摘要

上皮-间质转化（EMT）最早由伊丽莎白（贝蒂）·海博士于20世纪80年代在脊椎动物胚胎发育过程中描述[1]，在癌症侵袭性方面具有重要意义[2]。[...]