Division of Rheumatology, Department of Medicine, Mount Auburn Hospital, Cambridge, Massachusetts, USA.
Assistant Professor of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Clin Infect Dis. 2020 Dec 3;71(9):2482-2487. doi: 10.1093/cid/ciaa681.
Previous reports have suggested that transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is reduced by higher temperatures and higher humidity. We analyzed case data from the United States to investigate the effects of temperature, precipitation, and ultraviolet (UV) light on community transmission of SARS-CoV-2.
Daily reported cases of SARS-CoV-2 across the United States from 22 January 2020 to 3 April 2020 were analyzed. We used negative binomial regression modeling to determine whether daily maximum temperature, precipitation, UV index, and the incidence 5 days later were related.
A maximum temperature above 52°F on a given day was associated with a lower rate of new cases at 5 days (incidence rate ratio [IRR], 0.85 [0.76, 0.96]; P = .009). Among observations with daily temperatures below 52°F, there was a significant inverse association between the maximum daily temperature and the rate of cases at 5 days (IRR, 0.98 [0.97, 0.99]; P = .001). A 1-unit higher UV index was associated with a lower rate at 5 days (IRR, 0.97 [0.95, 0.99]; P = .004). Precipitation was not associated with a greater rate of cases at 5 days (IRR, 0.98 [0.89, 1.08]; P = .65).
The incidence of disease declines with increasing temperature up to 52°F and is lower at warmer vs cooler temperatures. However, the association between temperature and transmission is small, and transmission is likely to remain high at warmer temperatures.
之前的报告表明,较高的温度和湿度会降低严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的传播。我们分析了来自美国的数据,以调查温度、降水和紫外线(UV)对 SARS-CoV-2 社区传播的影响。
分析了 2020 年 1 月 22 日至 2020 年 4 月 3 日期间美国各地每日报告的 SARS-CoV-2 病例。我们使用负二项回归模型来确定每日最高温度、降水、UV 指数和 5 天后的发病率是否相关。
某一天的最高温度超过 52°F 与 5 天后的新病例率较低相关(发病率比 [IRR],0.85 [0.76,0.96];P =.009)。在每日温度低于 52°F 的观察中,最高日温度与 5 天内的病例率呈显著负相关(IRR,0.98 [0.97,0.99];P =.001)。UV 指数每增加 1 单位,5 天后的发病率就会降低(IRR,0.97 [0.95,0.99];P =.004)。降水与 5 天后的更高病例率无关(IRR,0.98 [0.89,1.08];P =.65)。
随着温度升高至 52°F,疾病的发病率下降,且在较暖的温度下发病率较低。然而,温度与传播之间的关联很小,在温暖的温度下,传播仍可能很高。