Emerg Infect Dis. 2021 Feb;27(2):421-429. doi: 10.3201/eid2702.204158. Epub 2021 Jan 4.
To assess transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a detention facility experiencing a coronavirus disease outbreak and evaluate testing strategies, we conducted a prospective cohort investigation in a facility in Louisiana, USA. We conducted SARS-CoV-2 testing for detained persons in 6 quarantined dormitories at various time points. Of 143 persons, 53 were positive at the initial test, and an additional 58 persons were positive at later time points (cumulative incidence 78%). In 1 dormitory, all 45 detained persons initially were negative; 18 days later, 40 (89%) were positive. Among persons who were SARS-CoV-2 positive, 47% (52/111) were asymptomatic at the time of specimen collection; 14 had replication-competent virus isolated. Serial SARS-CoV-2 testing might help interrupt transmission through medical isolation and quarantine. Testing in correctional and detention facilities will be most effective when initiated early in an outbreak, inclusive of all exposed persons, and paired with infection prevention and control.
为评估在爆发 2019 冠状病毒病（COVID-19）的拘留设施中严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的传播情况并评估检测策略，我们在美国路易斯安那州的一个设施中进行了一项前瞻性队列研究。我们在 6 个隔离宿舍中对被拘留者进行了 SARS-CoV-2 检测，时间点不同。在 143 人中，53 人在初始检测时呈阳性，随后又有 58 人呈阳性（累计发病率为 78%）。在一个宿舍中，最初 45 名被拘留者均呈阴性；18 天后，40 人（89%）呈阳性。在 SARS-CoV-2 阳性者中，47%（52/111）在采集样本时无症状；其中 14 人分离到有复制能力的病毒。连续进行 SARS-CoV-2 检测可能有助于通过医学隔离和检疫来中断传播。在爆发早期，对所有接触者进行检测，并结合感染预防和控制，对惩教和拘留设施进行检测将是最有效的。
