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[在可移植大鼠横纹肌肉瘤RA-2细胞群体中选择转移潜能降低的细胞]

[Selection for a decrease in metastatic potential in a cell population of transplantable rat rhabdomyosarcoma RA-2].

作者信息

Guzhova I V, Vakhtin Iu B

出版信息

Tsitologiia. 1988 Dec;30(12):1482-7.

PMID:3247682
Abstract

The method of individual cloning was used for checking the reduction of metastatic potential (MP) in cell population of highly malignant rhabdomyosarcoma RA-2. In the course of 15 selection cycles MP was lowered by 10-15 times. These data enabled us to consider the MP value as a quantitative character of malignant cells with low heritability (the mean value of realized heritability coefficient is equal to 0.18).

摘要

采用个体克隆方法检测高恶性横纹肌肉瘤RA-2细胞群体转移潜能（MP）的降低情况。在15个选择周期内，MP降低了10至15倍。这些数据使我们能够将MP值视为遗传性低的恶性细胞的定量特征（实现的遗传力系数平均值等于0.18）。

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Tsitologiia. 1988 Dec;30(12):1482-7.
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