Guzhova I V, Vakhtin Iu B
Tsitologiia. 1988 Dec;30(12):1482-7.
The method of individual cloning was used for checking the reduction of metastatic potential (MP) in cell population of highly malignant rhabdomyosarcoma RA-2. In the course of 15 selection cycles MP was lowered by 10-15 times. These data enabled us to consider the MP value as a quantitative character of malignant cells with low heritability (the mean value of realized heritability coefficient is equal to 0.18).
采用个体克隆方法检测高恶性横纹肌肉瘤RA-2细胞群体转移潜能(MP)的降低情况。在15个选择周期内,MP降低了10至15倍。这些数据使我们能够将MP值视为遗传性低的恶性细胞的定量特征(实现的遗传力系数平均值等于0.18)。