• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

7例隐源性机化性肺炎患者接受克拉霉素治疗后取得成功。

Seven patients with cryptogenic organizing pneumonia succesfully treated with clarithromycin.

作者信息

Ciftci Fatma, Kumbasar Özlem Özdemir

机构信息

Ankara University School of Medicine, Department of Chest Disease, Ankara, Turkey.

出版信息

Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(2):165-170. doi: 10.36141/svdld.v35i2.6887. Epub 2018 Apr 28.

DOI:10.36141/svdld.v35i2.6887
PMID:32476898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7170085/
Abstract

Cryptogenic organizing pneumonia is a type of idiopathic interstitial pneumonia with a subacute presentation characterized by variable degrees of cough and dyspnea. As a consequence of the upregulation of inflammatory mediators in cryptogenic organizing pneumonia, it typically responds to anti-inflammatory therapy. Although the majority of patients recover completely with long term oral corticosteroids, relapse is common and their long term use is associated with many adverse effects. Macrolides antiinflammatory agents that appear effective and safe for the treatment of cryptogenic organizing pneumonia. Herein, we analyzed the clinical properties of seven cryptogenic organizing pneumonia patients without severe functional loss who were treated with clarithromycin. .

摘要

隐源性机化性肺炎是一种特发性间质性肺炎,呈亚急性表现,其特征为不同程度的咳嗽和呼吸困难。由于隐源性机化性肺炎中炎症介质上调,它通常对抗炎治疗有反应。尽管大多数患者使用长期口服糖皮质激素可完全康复,但复发很常见,且长期使用会带来许多不良反应。大环内酯类抗炎药对隐源性机化性肺炎的治疗似乎有效且安全。在此,我们分析了7例接受克拉霉素治疗且无严重功能丧失的隐源性机化性肺炎患者的临床特征。

相似文献

1
Seven patients with cryptogenic organizing pneumonia succesfully treated with clarithromycin.7例隐源性机化性肺炎患者接受克拉霉素治疗后取得成功。
Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(2):165-170. doi: 10.36141/svdld.v35i2.6887. Epub 2018 Apr 28.
2
Macrolide use leads to clinical and radiological improvement in patients with cryptogenic organizing pneumonia.大环内酯类药物的使用可改善隐源性机化性肺炎患者的临床和影像学表现。
Ann Am Thorac Soc. 2014 Jan;11(1):87-91. doi: 10.1513/AnnalsATS.201308-261CR.
3
Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia.隐源性机化性肺炎患者对克拉霉素的不同反应
Tuberc Respir Dis (Seoul). 2015 Oct;78(4):401-7. doi: 10.4046/trd.2015.78.4.401. Epub 2015 Oct 1.
4
A long-term retrospective study of patients with biopsy-proven cryptogenic organizing pneumonia.经活检证实为隐源性机化性肺炎患者的长期回顾性研究。
Chron Respir Dis. 2019 Jan-Dec;16:1479973119853829. doi: 10.1177/1479973119853829.
5
A 12-week combination of clarithromycin and prednisone compared to a 24-week prednisone alone treatment in cryptogenic and radiation-induced organizing pneumonia.在隐源性和放射性诱导型机化性肺炎中,克拉霉素与泼尼松联合使用12周与单独使用泼尼松治疗24周的疗效比较。
Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(3):230-238. doi: 10.36141/svdld.v35i3.6547. Epub 2018 Apr 28.
6
[Cryptogenic organizing pneumonia versus secondary organizing pneumonia].[隐源性机化性肺炎与继发性机化性肺炎]
Pathologe. 2021 Feb;42(1):55-63. doi: 10.1007/s00292-020-00903-8. Epub 2021 Jan 18.
7
Successful treatment of three patients with organizing pneumonia associated with rheumatoid arthritis using clarithromycin and prednisolone.使用克拉霉素和泼尼松龙成功治疗3例类风湿关节炎相关的机化性肺炎患者。
Drug Discov Ther. 2017;11(4):218-222. doi: 10.5582/ddt.2017.01043.
8
Macrolides: a treatment alternative for bronchiolitis obliterans organizing pneumonia?大环内酯类药物:闭塞性细支气管炎并机化性肺炎的一种治疗选择?
Chest. 2005 Nov;128(5):3611-7. doi: 10.1378/chest.128.5.3611.
9
A Cryptogenic Case of Fulminant Fibrosing Organizing Pneumonia.一例暴发性纤维化性机化性肺炎的隐源性病例。
Intern Med. 2017;56(10):1185-1191. doi: 10.2169/internalmedicine.56.7371. Epub 2017 May 15.
10
Update on cryptogenic organizing pneumonia.隐源性机化性肺炎的最新进展
Front Med (Lausanne). 2023 Apr 20;10:1146782. doi: 10.3389/fmed.2023.1146782. eCollection 2023.

引用本文的文献

1
Update on cryptogenic organizing pneumonia.隐源性机化性肺炎的最新进展
Front Med (Lausanne). 2023 Apr 20;10:1146782. doi: 10.3389/fmed.2023.1146782. eCollection 2023.
2
Clarithromycin in Post COVID-19 Organizing pneumonia.克拉霉素在新冠后机化性肺炎中的应用
Sarcoidosis Vasc Diffuse Lung Dis. 2022;39(3):e2022025. doi: 10.36141/svdld.v39i3.13003. Epub 2022 Sep 23.
3
Transthoracic Ultrasound in Infectious Organizing Pneumonia: A Useful Guide for Percutaneous Needle Biopsy.经胸超声在感染性机化性肺炎中的应用:经皮穿刺活检的实用指南
Front Med (Lausanne). 2021 Jul 19;8:708937. doi: 10.3389/fmed.2021.708937. eCollection 2021.

本文引用的文献

1
Acute and subacute idiopathic interstitial pneumonias.急性和亚急性特发性间质性肺炎。
Respirology. 2016 Jul;21(5):810-20. doi: 10.1111/resp.12786. Epub 2016 Apr 28.
2
Cryptogenic Organizing Pneumonia: IL-1β, IL-6, IL-8, and TGF- β1 Serum Concentrations and Response to Clarithromycin Treatment.隐源性机化性肺炎:白细胞介素-1β、白细胞介素-6、白细胞介素-8和转化生长因子-β1血清浓度及对克拉霉素治疗的反应
Adv Exp Med Biol. 2016;911:77-85. doi: 10.1007/5584_2016_223.
3
Macrolide use leads to clinical and radiological improvement in patients with cryptogenic organizing pneumonia.大环内酯类药物的使用可改善隐源性机化性肺炎患者的临床和影像学表现。
Ann Am Thorac Soc. 2014 Jan;11(1):87-91. doi: 10.1513/AnnalsATS.201308-261CR.
4
Macrolides inhibit cytokine production by alveolar macrophages in bronchiolitis obliterans organizing pneumonia.大环内酯类药物抑制细支气管炎性闭塞性细支气管炎机化性肺炎肺泡巨噬细胞细胞因子的产生。
Immunobiology. 2013 Jun;218(6):930-7. doi: 10.1016/j.imbio.2012.10.014. Epub 2012 Nov 2.
5
Successful salvage treatment of steroid-refractory bronchiolar COP with low-dose macrolides.成功应用小剂量大环内酯类药物抢救治疗激素抵抗性细支气管炎型COP
Pathol Int. 2012 Feb;62(2):144-8. doi: 10.1111/j.1440-1827.2011.02766.x. Epub 2011 Nov 30.
6
Adjunctive effects of cyclosporine and macrolide in rapidly progressive cryptogenic organizing pneumonia with no prompt response to steroid.环孢素和大环内酯类药物在对类固醇治疗无迅速反应的快速进展性隐源性机化性肺炎中的辅助作用。
Intern Med. 2011;50(5):475-9. doi: 10.2169/internalmedicine.50.4237. Epub 2011 Mar 1.
7
Macrolides beyond the conventional antimicrobials: a class of potent immunomodulators.超越传统抗菌药物的大环内酯类药物:一类强效免疫调节剂。
Int J Antimicrob Agents. 2008 Jan;31(1):12-20. doi: 10.1016/j.ijantimicag.2007.08.001. Epub 2007 Nov 1.
8
Cryptogenic organising pneumonia.隐源性机化性肺炎
Eur Respir J. 2006 Aug;28(2):422-46. doi: 10.1183/09031936.06.00013505.
9
Macrolides: a treatment alternative for bronchiolitis obliterans organizing pneumonia?大环内酯类药物:闭塞性细支气管炎并机化性肺炎的一种治疗选择?
Chest. 2005 Nov;128(5):3611-7. doi: 10.1378/chest.128.5.3611.
10
Anti-inflammatory effects of macrolides--an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions?大环内酯类药物的抗炎作用——在社区获得性呼吸道感染和慢性炎症性肺部疾病治疗中未被充分认识的益处?
J Antimicrob Chemother. 2005 Jan;55(1):10-21. doi: 10.1093/jac/dkh519. Epub 2004 Dec 8.