Leshchuk S I
Vopr Virusol. 1988 Nov-Dec;33(6):722-5.
The nature of nonspecific reactions observed in reverse passive hemagglutination test was studied. Nonspecific reactions were found to be associated with the use of different ingredients in construction of immunodiagnostic preparations for HBs antigen and with the presence in the examined sera of heterologous hemagglutinins, rheumatoid factor, and bacterial contamination. Therefore, positive results of hemagglutination should be verified for specificity by neutralization tests with HBs antigen.
对反向被动血凝试验中观察到的非特异性反应的性质进行了研究。发现非特异性反应与用于构建乙肝表面抗原免疫诊断制剂的不同成分的使用有关，也与受检血清中存在的异种血凝素、类风湿因子和细菌污染有关。因此，血凝试验的阳性结果应用乙肝表面抗原中和试验来验证其特异性。
