• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

DAT1 Gene Methylation as an Epigenetic Biomarker in Attention Deficit Hyperactivity Disorder: A Commentary.

作者信息

Tonelli Erika, Pascale Esterina, Troianiello Miriam, D'Addario Claudio, Adriani Walter

机构信息

Faculty of Psychology, Università Telematica Internazionale "Uninettuno", Rome, Italy.

Medico-Surgical Sciences and Biotechnologies Department, "Sapienza" University of Rome, Rome, Italy.

出版信息

Front Genet. 2020 May 11;11:444. doi: 10.3389/fgene.2020.00444. eCollection 2020.

DOI:10.3389/fgene.2020.00444
PMID:32477403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7232962/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec5a/7232962/2abca4789b6e/fgene-11-00444-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec5a/7232962/2abca4789b6e/fgene-11-00444-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec5a/7232962/2abca4789b6e/fgene-11-00444-g0001.jpg

相似文献

1
DAT1 Gene Methylation as an Epigenetic Biomarker in Attention Deficit Hyperactivity Disorder: A Commentary.多巴胺转运体1基因甲基化作为注意缺陷多动障碍的一种表观遗传生物标志物:一篇评论
Front Genet. 2020 May 11;11:444. doi: 10.3389/fgene.2020.00444. eCollection 2020.
2
Potential for diagnosis versus therapy monitoring of attention deficit hyperactivity disorder: a new epigenetic biomarker interacting with both genotype and auto-immunity.注意缺陷多动障碍的诊断与治疗监测潜力:与基因型和自身免疫相互作用的新型表观遗传生物标志物。
Eur Child Adolesc Psychiatry. 2018 Feb;27(2):241-252. doi: 10.1007/s00787-017-1040-9. Epub 2017 Aug 18.
3
Search for an epigenetic biomarker in ADHD diagnosis, based on the DAT1 gene 5'-UTR methylation: a new possible approach.基于 DAT1 基因 5'-UTR 甲基化寻找 ADHD 诊断中的表观遗传生物标志物:一种新的可能方法。
Psychiatry Res. 2020 Sep;291:113154. doi: 10.1016/j.psychres.2020.113154. Epub 2020 May 30.
4
DAT1 methylation is associated with methylphenidate response on oppositional and hyperactive-impulsive symptoms in children and adolescents with ADHD.多巴胺转运体1(DAT1)甲基化与注意缺陷多动障碍(ADHD)儿童及青少年对立违抗和多动冲动症状对哌甲酯的反应相关。
World J Biol Psychiatry. 2017 Jun;18(4):291-299. doi: 10.1080/15622975.2016.1224928. Epub 2016 Sep 27.
5
Methylation Dynamics on 5'-UTR of Gene as a Bio-Marker to Recognize Therapy Success in ADHD Children.基因5'-非翻译区的甲基化动态作为识别多动症儿童治疗成功的生物标志物
Children (Basel). 2023 Mar 18;10(3):584. doi: 10.3390/children10030584.
6
Methylation of the dopamine transporter gene in blood is associated with striatal dopamine transporter availability in ADHD: A preliminary study.血液中多巴胺转运体基因的甲基化与 ADHD 患者纹状体多巴胺转运体的可利用性相关:一项初步研究。
Eur J Neurosci. 2018 Aug;48(3):1884-1895. doi: 10.1111/ejn.14067.
7
Effects of the dopamine transporter gene on neuroimaging findings in different attention deficit hyperactivity disorder presentations.多巴胺转运体基因对不同注意缺陷多动障碍表现的神经影像学发现的影响。
Brain Imaging Behav. 2021 Apr;15(2):1103-1114. doi: 10.1007/s11682-020-00437-w. Epub 2021 Jan 20.
8
DNA Methylation in and Genes Is Associated with Attention Deficit in Children.某些基因中的DNA甲基化与儿童注意力缺陷有关。 (注:原文中“in and Genes”表述不完整,可能有信息缺失)
Children (Basel). 2021 Jan 29;8(2):92. doi: 10.3390/children8020092.
9
5'-Un-Translated-Region Methylation Patterns as Bio-Markers of ADHD Psycho-Pathology: Contribution to Disease Prognosis and to Monitoring of a Successful Therapy.5'-非翻译区甲基化模式作为注意力缺陷多动障碍心理病理学的生物标志物:对疾病预后和成功治疗监测的贡献
Biomedicines. 2023 Sep 15;11(9):2546. doi: 10.3390/biomedicines11092546.
10
Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder.多巴胺转运体(DAT1)基因型、左侧注意力不集中与注意缺陷多动障碍患者对哌甲酯反应增强之间的关联。
Neuropsychopharmacology. 2005 Dec;30(12):2290-7. doi: 10.1038/sj.npp.1300839.

引用本文的文献

1
Dopamine in Sports: A Narrative Review on the Genetic and Epigenetic Factors Shaping Personality and Athletic Performance.多巴胺与运动:塑造个性和运动表现的遗传与表观遗传因素的叙述性综述。
Int J Mol Sci. 2024 Oct 29;25(21):11602. doi: 10.3390/ijms252111602.
2
Association of HHV‑6 reactivation and SLC6A3 (C>T, rs40184), BDNF (C>T, rs6265), and JARID2 (G>A, rs9383046) single nucleotide polymorphisms in depression.抑郁症中HHV-6再激活与SLC6A3(C>T,rs40184)、BDNF(C>T,rs6265)及JARID2(G>A,rs9383046)单核苷酸多态性的关联
Biomed Rep. 2024 Oct 3;21(6):181. doi: 10.3892/br.2024.1869. eCollection 2024 Dec.
3

本文引用的文献

1
Search for an epigenetic biomarker in ADHD diagnosis, based on the DAT1 gene 5'-UTR methylation: a new possible approach.基于 DAT1 基因 5'-UTR 甲基化寻找 ADHD 诊断中的表观遗传生物标志物:一种新的可能方法。
Psychiatry Res. 2020 Sep;291:113154. doi: 10.1016/j.psychres.2020.113154. Epub 2020 May 30.
2
Potential for diagnosis versus therapy monitoring of attention deficit hyperactivity disorder: a new epigenetic biomarker interacting with both genotype and auto-immunity.注意缺陷多动障碍的诊断与治疗监测潜力:与基因型和自身免疫相互作用的新型表观遗传生物标志物。
Eur Child Adolesc Psychiatry. 2018 Feb;27(2):241-252. doi: 10.1007/s00787-017-1040-9. Epub 2017 Aug 18.
3
Correlation of the methylomic signature of smoking during pregnancy with clinical traits in ADHD.
妊娠期吸烟的甲基化特征与 ADHD 临床特征的相关性。
J Psychiatry Neurosci. 2023 Oct 19;48(5):E390-E399. doi: 10.1503/jpn.230062. Print 2023 Sep-Oct.
4
Attention Deficit-Hyperactivity Disorder (ADHD): From Abnormal Behavior to Impairment in Synaptic Plasticity.注意力缺陷多动障碍(ADHD):从异常行为到突触可塑性损伤
Biology (Basel). 2023 Sep 15;12(9):1241. doi: 10.3390/biology12091241.
5
How Can CpG Methylations, and Pair-to-Pair Correlations between the Main (Gene) and the Opposite Strands, Suggest a Bending DNA Loop: Insights into the 5'-UTR of DAT1.CpG 甲基化如何以及主链(基因)与相反链之间的配对相关性提示 DNA 环弯曲:DAT1 的 5'-UTR 分析。
Genes (Basel). 2023 Jan 11;14(1):190. doi: 10.3390/genes14010190.
6
A mechanistic model of ADHD as resulting from dopamine phasic/tonic imbalance during reinforcement learning.一种将注意力缺陷多动障碍(ADHD)归因于强化学习过程中多巴胺相位/张力失衡的机制模型。
Front Comput Neurosci. 2022 Jul 18;16:849323. doi: 10.3389/fncom.2022.849323. eCollection 2022.
7
Methylation in the Promoter Region of the Dopamine Transporter Gene in People Addicted to Nicotine.尼古丁成瘾者多巴胺转运体基因启动子区的甲基化。
Int J Environ Res Public Health. 2022 Jul 14;19(14):8602. doi: 10.3390/ijerph19148602.
8
Animal Models of ADHD?ADHD 的动物模型?
Curr Top Behav Neurosci. 2022;57:363-393. doi: 10.1007/7854_2022_342.
9
Involvement of DAT1 Gene on Internet Addiction: Cross-Correlations of Methylation Levels in 5'-UTR and 3'-UTR Genotypes, Interact with Impulsivity and Attachment-Driven Quality of Relationships.DAT1 基因与网络成瘾的关系:5'UTR 和 3'UTR 基因型甲基化水平的交叉相关性,与冲动和依恋驱动的人际关系质量相互作用。
Int J Environ Res Public Health. 2020 Oct 29;17(21):7956. doi: 10.3390/ijerph17217956.
Brain imaging genetics in ADHD and beyond - Mapping pathways from gene to disorder at different levels of complexity.
注意缺陷多动障碍及其他相关疾病的脑影像遗传学:在不同复杂程度的水平上从基因到疾病的映射途径。
Neurosci Biobehav Rev. 2017 Sep;80:115-155. doi: 10.1016/j.neubiorev.2017.01.013. Epub 2017 Jan 31.
4
A preliminary study of endocannabinoid system regulation in psychosis: Distinct alterations of CNR1 promoter DNA methylation in patients with schizophrenia.精神分裂症中内源性大麻素系统调节的初步研究:精神分裂症患者中 CNR1 启动子 DNA 甲基化的明显改变。
Schizophr Res. 2017 Oct;188:132-140. doi: 10.1016/j.schres.2017.01.022. Epub 2017 Jan 17.
5
Gilles de la Tourette syndrome is associated with hypermethylation of the dopamine D2 receptor gene.抽动秽语综合征与多巴胺D2受体基因的高甲基化有关。
J Psychiatr Res. 2017 Mar;86:1-8. doi: 10.1016/j.jpsychires.2016.11.004. Epub 2016 Nov 12.
6
Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children.儿童注意力缺陷多动障碍中DRD4基因的表观遗传调控及相关维度
Eur Child Adolesc Psychiatry. 2016 Oct;25(10):1081-9. doi: 10.1007/s00787-016-0828-3. Epub 2016 Feb 20.
7
Multiple epigenetic factors predict the attention deficit/hyperactivity disorder among the Chinese Han children.多种表观遗传因素可预测中国汉族儿童的注意力缺陷多动障碍。
J Psychiatr Res. 2015 May;64:40-50. doi: 10.1016/j.jpsychires.2015.03.006. Epub 2015 Mar 22.
8
Detection of auto-antibodies to DAT in the serum: interactions with DAT genotype and psycho-stimulant therapy for ADHD.血清中针对多巴胺转运体(DAT)自身抗体的检测:与DAT基因型及多动症精神兴奋剂治疗的相互作用
J Neuroimmunol. 2015 Jan 15;278:212-22. doi: 10.1016/j.jneuroim.2014.11.008. Epub 2014 Nov 18.
9
Imaging the ADHD brain: disorder-specificity, medication effects and clinical translation.对注意力缺陷多动障碍患者大脑的成像研究:疾病特异性、药物作用及临床转化
Expert Rev Neurother. 2014 May;14(5):519-38. doi: 10.1586/14737175.2014.907526. Epub 2014 Apr 17.
10
Reversing DNA methylation: mechanisms, genomics, and biological functions.逆转 DNA 甲基化:机制、基因组学和生物学功能。
Cell. 2014 Jan 16;156(1-2):45-68. doi: 10.1016/j.cell.2013.12.019.