Ruvalcaba-Cardenas Ana Daysi, Gomez Raul Alejandro Ramirez, Khoshmanesh Khashayar, Tovar-Lopez Francisco J
School of Engineering, RMIT University, Melbourne, Victoria 3000, Australia.
Biomicrofluidics. 2020 May 18;14(3):034103. doi: 10.1063/5.0008176. eCollection 2020 May.
Here, we describe the magnetic actuation of soft shuttles for open-top microfluidic applications. The system is comprised of two immiscible liquids, including glycerol as the soft shuttle and a suspension of iron powder in sucrose solution as the magnetic drop. Permanent magnets assembled on 3D printed motorized actuators were used for the actuation of the magnetic drop, enabling the glycerol shuttle to be propelled along customized linear, circular, and sinusoidal paths. The dynamics of the hybrid shuttle-magnetic drop system was governed by the magnetic force, the friction at the interface of the shuttle and the substrate, and the surface tension at the interface of the shuttle and the magnetic drop. Increasing the magnetic force leads to the localized deformation of the shuttle and eventually the full extraction of the magnetic drop. The versatility of the system was demonstrated through the propelling of the shuttle across a rough surface patterned with microfabricated barriers as well as taking advantage of the optical properties of the shuttle for the magnification and translation of microscale characters patterned on a planar surface. The integration of the system with current electrowetting actuation mechanisms enables the highly controlled motion of the magnetic drop on the surface of a moving shuttle. The simplicity, versatility, and controllability of the system provide opportunities for various fluid manipulation, sample preparation, and analysis for a range of chemical, biochemical, and biological applications.
在此，我们描述了用于顶部开放微流体应用的软穿梭器的磁驱动。该系统由两种互不相溶的液体组成，包括作为软穿梭器的甘油和作为磁滴的蔗糖溶液中的铁粉悬浮液。组装在3D打印电动致动器上的永磁体用于驱动磁滴，使甘油穿梭器能够沿着定制的线性、圆形和正弦路径推进。混合穿梭器 - 磁滴系统的动力学受磁力、穿梭器与基底界面处的摩擦力以及穿梭器与磁滴界面处的表面张力支配。增加磁力会导致穿梭器局部变形，最终使磁滴完全抽出。该系统的多功能性通过使穿梭器在带有微加工障碍物图案的粗糙表面上推进以及利用穿梭器的光学特性对平面上图案化的微尺度字符进行放大和移位得以证明。该系统与当前的电润湿驱动机制相结合，能够高度控制磁滴在移动穿梭器表面上的运动。该系统的简单性、多功能性和可控性为一系列化学、生化和生物应用中的各种流体操作、样品制备和分析提供了机会。
