Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China; Pharmacy College, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
Biosens Bioelectron. 2020 Sep 15;164:112255. doi: 10.1016/j.bios.2020.112255. Epub 2020 Apr 30.
Immunosensors for rapid detection of pesticide residues has attracted considerable interest in the past few years for healthcare and environmental monitoring. And the publications have grown exponentially over the past decades, making it a trending hot-spot. Therefore, this review first examines the current situation regarding pesticide residue in various foods, feeds, traditional Chinese medicines and environmental samples. Then, the primary focus is on the recent development of the proposed immunosensors for pesticide detection in the past five years, with particular emphasis on the fluorescence, colorimetric, chemiluminescence, electrochemiluminescence, surface plasmon resonance, surface-enhanced Raman spectroscopy, electrochemical and piezoelectric sensors. Beyond a highlight of the real-world application and advantages of these emerging immunosensors for pesticide inspection, this paper also discusses their potential limits and current challenges, as well as future perspectives. This review will provide powerful insights to researchers for the future development of immunosensors, as well as their broader application in different fields, such as analytical chemistry, food safety control, clinical diagnostics, and environmental monitoring.
在过去的几年中，用于快速检测农药残留的免疫传感器在医疗保健和环境监测领域引起了相当大的关注。在过去的几十年中，相关出版物呈指数级增长，成为一个热门话题。因此，本文首先考察了各种食品、饲料、中药和环境样品中农药残留的现状。然后，主要关注过去五年中提出的用于农药检测的免疫传感器的最新发展，特别强调荧光、比色、化学发光、电致化学发光、表面等离子体共振、表面增强拉曼光谱、电化学和压电传感器。除了强调这些新兴免疫传感器在农药检测中的实际应用和优势外，本文还讨论了它们的潜在局限性和当前挑战，以及未来展望。本文将为研究人员提供有关免疫传感器未来发展的深刻见解，以及它们在分析化学、食品安全控制、临床诊断和环境监测等不同领域的更广泛应用。
