Department of Disease Control, Center for Disease Control and Prevention in Northern Theater Command, Shenyang, Liaoning, China.
PLoS One. 2020 Jun 1;15(6):e0232948. doi: 10.1371/journal.pone.0232948. eCollection 2020.
An outbreak of respiratory disease associated with adenovirus type 7 occurred in a boot camp in China and was characterized by many cases, severe symptoms, and intrapulmonary infection in many patients.
We implemented a series of comprehensive preventive and control measures. We analyzed the incubation period and generation time by using the maximum likelihood method, assessed the symptom period and hospitalization duration using the Kaplan-Meier method, and estimated the basic reproductive number and dormitory transmission rate by using established methods.
The epidemic lasted for 30 days, and 375 individuals were affected. Overall, 109 patients were hospitalized, and 266 individuals were isolated and treated. The median incubation period was 5.2 days (95% confidence interval [CI]: 5.0 to 5.4 days). The median generation time was 7.3 days (95% CI: 7.1 to 7.6 days). The median symptom period was 6 days (95% CI: 6 to 7 days). The median hospitalization duration was 9 days (95% CI: 9 to 11 days). The basic reproductive number was 5.1 (95% CI: 4.6 to 5.6), and the dormitory transmission rate was 0.15 (95% CI: 0.12 to 0.18).
Patients in the early stage of the epidemic were treated as having a regular cold and were not isolated; therefore, the virus continued to be transmitted to other susceptible individuals.
中国某新兵训练营发生了一起与腺病毒 7 型相关的呼吸道疾病暴发疫情，其特点是发病人数多、症状重、多为肺部感染。
我们实施了一系列综合防控措施。采用最大似然法分析潜伏期和代间距，用 Kaplan-Meier 法分析症状期和住院时间，采用已建立的方法估计基本再生数和宿舍内传播率。
该疫情持续 30 天，共发病 375 例。总体上有 109 例住院，266 例隔离治疗。潜伏期中位数为 5.2 天（95%可信区间：5.05.4 天）。代间距中位数为 7.3 天（95%可信区间：7.17.6 天）。症状期中位数为 6 天（95%可信区间：67 天）。住院时间中位数为 9 天（95%可信区间：911 天）。基本再生数为 5.1（95%可信区间：4.65.6），宿舍内传播率为 0.15（95%可信区间：0.120.18）。
疫情早期患者被当作普通感冒对待且未进行隔离，导致病毒继续传播给其他易感者。
