Plasma Oncology Laboratory, Department of Urology, University Medicine Greifswald, Greifswald, Germany.
Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany.
Health Phys. 2020 Jul;119(1):153-159. doi: 10.1097/HP.0000000000001276.
The generation of cold physical plasma at atmospheric pressure (cold atmospheric plasma: CAP) generates different reactive molecular species as well as radiation in the ultraviolet (UV) range. The therapy of tumor diseases has proven to be a new promising area of application for CAP treatment. With regard to the routine use of CAP in cancer therapy, however, application safety must be ensured both for the patient and for the operator. In this study, the intensity of UVC radiation of the CAP device MiniJet-R (HF Technik, Aachen, Germany) was measured in the range from 220 to 280 nm depending on various device-specific parameters. Depending on the distance to the CAP flame, the UVC intensity reaches values up to 124.5±11 mW m. It should be noted here that the UVC radiation generated by the CAP is emitted in all orientations in the room but is also shielded by the geometry of the handpiece of the CAP device. The device-specific settings for the flow rate of the carrier gas, argon, and the power level at the high-frequency (HF) generator of the CAP device also influence the intensity of the UVC radiation. With regard to the medical use of the CAP device, it can be stated that there is an exposure to UVC radiation, which, depending on the duration of treatment, can also be above the maximum value legally specified in Europe. Shielding components on the CAP device can reduce UVC exposure to the operator as well as adverse side effects to the patient.
大气压冷等离子体（CAP）的产生会产生不同的反应分子种类以及紫外线（UV）范围内的辐射。肿瘤疾病的治疗已被证明是 CAP 治疗的一个有前途的新应用领域。然而，关于 CAP 在癌症治疗中的常规使用，必须确保患者和操作人员的应用安全。在这项研究中，根据各种设备特定参数，在 220nm 至 280nm 范围内测量了 HF Technik（德国亚琛）生产的 MiniJet-R 型 CAP 设备的 UVC 辐射强度。根据与 CAP 火焰的距离，UVC 强度可达到 124.5±11mW m。需要注意的是，CAP 产生的 UVC 辐射以所有方向在房间中发射，但也被 CAP 设备的手柄几何形状屏蔽。载气（氩气）的设备特定流速和 CAP 设备高频（HF）发生器的功率水平的设备特定设置也会影响 UVC 辐射的强度。就 CAP 设备的医疗用途而言，可以说存在 UVC 辐射暴露，根据治疗持续时间，其辐射暴露也可能超过欧洲规定的最大限值。CAP 设备上的屏蔽部件可以减少操作人员的 UVC 暴露以及对患者的不良副作用。
