Târgu Mureș Emergency Clinical Hospital, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142 Târgu Mureș, Romania.
Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Mar Drugs. 2020 May 31;18(6):290. doi: 10.3390/md18060290.
While terrestrial organisms are the primary source of natural products, recent years have witnessed a considerable shift towards marine-sourced biocompounds. They have achieved a great scientific interest due to the plethora of compounds with structural and chemical properties generally not found in terrestrial products, exhibiting significant bioactivity ten times higher than terrestrial-sourced molecules. In addition to the antioxidant, anti-thrombotic, anti-coagulant, anti-inflammatory, anti-proliferative, anti-hypertensive, anti-diabetic, and cardio-protection properties, marine-sourced biocompounds have been investigated for their neuroprotective potential. Thus, this review aims to describe the recent findings regarding the neuroprotective effects of the significant marine-sourced biocompounds.
虽然陆生生物是天然产物的主要来源，但近年来，人们越来越关注海洋来源的生物化合物。这些化合物具有丰富的结构和化学特性，通常在陆生产物中找不到，并且具有显著的生物活性，是陆生来源分子的十倍以上，因此引起了科学界的极大兴趣。除了具有抗氧化、抗血栓、抗凝血、抗炎、抗增殖、抗高血压、抗糖尿病和心脏保护作用外，人们还研究了海洋来源的生物化合物的神经保护潜力。因此，本综述旨在描述关于重要海洋来源生物化合物的神经保护作用的最新发现。
