Udayasankar Madhumita, Udupi Sandesh, Shenoy Anitha
Department of Anaesthesiology, Kasturba Medical College and Hospital, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Indian J Anaesth. 2020 Apr;64(4):316-321. doi: 10.4103/ija.IJA_782_19. Epub 2020 Mar 28.
Perioperative anxiety, hunger, thirst, fatigue, pain along with nausea and vomiting can influence a patient's recovery after surgery. We aimed to compare 'enhanced recovery after surgery' (ERAS) protocol with a traditional perioperative approach to evaluate a patient's recovery after elective laparoscopic cholecystectomy.
A prospective randomised controlled study was conducted after institutional ethical clearance on 50 patients undergoing elective laparoscopic cholecystectomy, and divided equally into two groups. In group 1 (traditional); standard fasting guidelines and routine perioperative management was implemented. In group 2 (ERAS); patients received appropriate multimedia information about surgery and anaesthesia besidecarbohydrate loading with tender coconut water on the previous night and on the morning of surgery. Standard guidelines of fasting for solids were followed. Intraoperatively, goal-directed fluid therapy and an inspired oxygen concentration of 60% were administered. Postoperatively, early diet and mobilisation were initiated. The primary outcome was the assessment of perioperative anxiety. Hunger, thirst, fatigue, pain, nausea, vomiting and overall perioperative experience were also evaluated.
ERAS group had reduced anxiety prior to surgery: median (interquartile range) 3 (3-4) vs 2 (2-3) ( = 0.003), and at 6 h postoperatively: 4 (3-6) vs 3 (1-4) ( = 0.001). Hunger, thirst and fatigue ( < 0.01) were also decreased with better overall perioperative experience (5 [4-5] vs 6 [5-7], = 0.004). Pain, nausea, vomiting and blood glucose were similar between the groups.
'ERAS approach reduces anxiety in addition to hunger, thirst and fatigue with enhanced overall perioperative comfort in patients undergoing laparoscopic cholecystectomy.
围手术期的焦虑、饥饿、口渴、疲劳、疼痛以及恶心和呕吐会影响患者术后的恢复。我们旨在比较“术后加速康复”(ERAS)方案与传统围手术期方法,以评估择期腹腔镜胆囊切除术后患者的恢复情况。
在获得机构伦理批准后,对50例行择期腹腔镜胆囊切除术的患者进行了一项前瞻性随机对照研究,并将其平均分为两组。第1组(传统组);实施标准禁食指南和常规围手术期管理。第2组(ERAS组);患者在术前一晚和手术当天早晨除了饮用嫩椰子水进行碳水化合物负荷外,还接受了有关手术和麻醉的适当多媒体信息。遵循固体食物的标准禁食指南。术中,实施目标导向液体治疗并给予60%的吸氧浓度。术后,尽早开始饮食和活动。主要结局是围手术期焦虑的评估。还评估了饥饿、口渴、疲劳、疼痛、恶心、呕吐和总体围手术期体验。
ERAS组术前焦虑减轻:中位数(四分位间距)为3(3 - 4)对2(2 - 3)(P = 0.003),术后6小时为4(3 - 6)对3(1 - 4)(P = 0.001)。饥饿、口渴和疲劳(P < 0.01)也有所减轻,总体围手术期体验更好(5[4 - 5]对6[5 - 7],P = 0.004)。两组之间疼痛、恶心、呕吐和血糖相似。
“ERAS方法除了减轻饥饿、口渴和疲劳外,还能减轻焦虑,提高腹腔镜胆囊切除患者围手术期的总体舒适度。