冷冻探头活检用于诊断病因不明的急性低氧性呼吸衰竭。
Cryoprobe biopsy for the diagnosis of acute hypoxemic respiratory failure of undetermined origin.
作者信息
Heras Marcos J Las, Dianti Jose, Tisminetzky Manuel, Svetliza Graciela, Giannasi Sergio E, Roman Eduardo San
机构信息
Servicio de Terapia Intensiva de Adultos, Hospital Italiano de Buenos Aires, Peron, Argentina.
Servicio de Clínica Médica, Sección de Neumonología, Hospital Italiano de Buenos Aires, Peron, Argentina.
出版信息
J Intensive Care Soc. 2020 May;21(2):119-123. doi: 10.1177/1751143719847323. Epub 2019 May 7.
RATIONALE
Acute hypoxemic respiratory failure is a condition that comprises a wide array of entities. Obtaining a histological lung sample might help reach a diagnosis and direct an appropriate treatment in a select group of patients.
OBJECTIVE
To describe our experience in the use of cryobiopsy for the diagnosis of acute hypoxemic respiratory failure of undetermined origin.
METHODS
Retrospective analysis of case series of patients with acute hypoxemic respiratory failure who underwent lung cryobiopsy at the Intensive Care Unit of the Hospital Italiano de Buenos Aires, Argentina.
RESULTS
Cryobiopsy yielded a histological diagnosis in all patients ( = 10, 100%). This led to either a change in therapy or continuation of a specific treatment in eight of these patients. Cryobiopsy was found to be contributive in all the patients who did not meet Berlin criteria for acute respiratory distress syndrome. No major complications were associated with the procedure.
CONCLUSIONS
Cryobiopsy is a safe procedure with a high diagnostic yield in a selected group of patients.
原理
急性低氧性呼吸衰竭是一种包含多种病症的情况。获取肺部组织学样本可能有助于在特定患者群体中做出诊断并指导适当的治疗。
目的
描述我们使用冷冻活检诊断不明原因急性低氧性呼吸衰竭的经验。
方法
对在阿根廷布宜诺斯艾利斯意大利医院重症监护病房接受肺部冷冻活检的急性低氧性呼吸衰竭患者的病例系列进行回顾性分析。
结果
冷冻活检在所有患者（n = 10，100%）中均得出组织学诊断。这导致其中8名患者的治疗发生改变或继续进行特定治疗。发现冷冻活检对所有不符合急性呼吸窘迫综合征柏林标准的患者都有帮助。该操作未出现重大并发症。
结论
冷冻活检是一种安全的操作，在特定患者群体中具有较高的诊断率。
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