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甲状腺转移瘤提示肺腺癌。

Thyroid metastasis revealing a lung adenocarcinoma.

作者信息

Ben Saad Ahmed, Mhamed Saousen Cheikh, Migaou Asma, Njima Manel, Achour Asma, Fahem Nesrine, Rouatbi Naceur, Joobeur Samah

机构信息

Pulmonology Department, Fattouma Bourguiba Hospital, Monastir, Tunisia.

Department of Pathology, Fattouma Bourguiba Hospital, Monastir, Tunisia.

出版信息

Respir Med Case Rep. 2020 May 16;30:101065. doi: 10.1016/j.rmcr.2020.101065. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101065
PMID:32489846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7256324/
Abstract

Thyroid metastasis revealing a primary lung cancer is an extremely rare condition. Only few cases have been reported in the literature. A multidisciplinary approach is essential for the diagnosis. The prognosis is generally poor. We report a case of a 50-year-old man presented with cervical nodules corresponding to a thyroid nodule and lymph nodes. The ultrasonography-guided fine-needle aspiration cytology of the thyroid nodule and a cervical lymphadenopathy concluded to a poorly differentiated adenocarcinoma. Cervical lymphadenopathy biopsy with immunohistochemistry and additional imaging explorations contributed to the diagnosis of a lung adenocarcinoma stage IVB. He died few days after the diagnosis.

摘要

甲状腺转移瘤揭示原发性肺癌是一种极其罕见的情况。文献中仅报道了少数病例。多学科方法对于诊断至关重要。预后通常较差。我们报告一例50岁男性,其颈部结节对应甲状腺结节和淋巴结。甲状腺结节及颈部淋巴结病的超声引导下细针穿刺细胞学检查结果为低分化腺癌。颈部淋巴结病活检及免疫组化检查和其他影像学检查有助于诊断IVB期肺腺癌。他在诊断后几天死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a88/7256324/bce0600c9cf3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a88/7256324/9b0a0caf8250/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a88/7256324/bce0600c9cf3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a88/7256324/9b0a0caf8250/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a88/7256324/bce0600c9cf3/gr2.jpg

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本文引用的文献

1
Thyroid metastasis from non-small cell lung cancer.非小细胞肺癌的甲状腺转移
Int J Clin Exp Pathol. 2019 Aug 1;12(8):3013-3021. eCollection 2019.
2
Nonthyroidal metastatic lesion in thyroid: A missed diagnosis and a lesson learnt.
J Cancer Res Ther. 2019 Jul-Sep;15(3):665-668. doi: 10.4103/jcrt.JCRT_1043_16.
3
Lung adenocarcinoma with thyroid metastasis: a case report.肺腺癌伴甲状腺转移:一例报告。
BMC Res Notes. 2017 Mar 21;10(1):130. doi: 10.1186/s13104-017-2449-4.
4
A case of synchronous isolated thyroid metastasis from a primary lung cancer presenting as thyroid primary: Diagnostic challenge!一例以甲状腺原发性表现的原发性肺癌同步孤立性甲状腺转移病例:诊断挑战!
Lung India. 2016 May-Jun;33(3):326-9. doi: 10.4103/0970-2113.180912.
5
Thyroid metastasis from small cell lung carcinoma: a case report and review of the literature.小细胞肺癌甲状腺转移:一例报告并文献复习
J Med Case Rep. 2015 Oct 7;9:231. doi: 10.1186/s13256-015-0707-4.
6
Isolated thyroid metastasis revealed an unknown lung adenocarcinoma: a case report.孤立性甲状腺转移瘤提示为未知的肺腺癌:一例报告
J Med Case Rep. 2015 Sep 27;9:221. doi: 10.1186/s13256-015-0663-z.
7
Fine-needle aspiration biopsy of secondary neoplasms of the thyroid gland: a multi-institutional study of 62 cases.甲状腺继发恶性肿瘤的细针穿刺活检:62 例多机构研究。
Cancer Cytopathol. 2015 Jan;123(1):19-29. doi: 10.1002/cncy.21494. Epub 2014 Nov 4.
8
Metastases to the thyroid: a review of the literature from the last decade.甲状腺转移:对过去十年文献的回顾。
Thyroid. 2012 Mar;22(3):258-68. doi: 10.1089/thy.2010.0154. Epub 2012 Feb 7.
9
Lung cancer, thyroid cancer or both: An unusual case presentation.肺癌、甲状腺癌还是两者都有:一个不寻常的病例报告。
J Thorac Dis. 2011 Dec;3(4):271-3. doi: 10.3978/j.issn.2072-1439.2011.02.03.
10
Metastasis to the thyroid diagnosed by fine-needle aspiration biopsy.通过细针穿刺活检诊断为甲状腺转移。
Clin Endocrinol (Oxf). 2005 Feb;62(2):236-41. doi: 10.1111/j.1365-2265.2005.02206.x.