Department of Pediatrics, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI.
Hawaii J Health Soc Welf. 2020 May 1;79(5 Suppl 1):3-6.
As one of 17 clinical sites of the Environmental influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (ISPCTN), the Hawai'i IDeA Center for Pediatric and Adolescent Clinical Trials (HIPACT) was established in 2016 to participate in community-valued and scientifically-valid multi-center pediatric clinical trials to improve health and well-being of diverse multi-ethnic populations of Hawai'i. Hawai'i is home to large populations of diverse rural and underserved populations, including indigenous Hawaiian communities and immigrant populations of Pacific Islanders and Asians. Many of these communities experience significant health disparities, made worse by their geographic isolation and many socio-economic factors. In addition to providing opportunities for children and their families to participate in clinical trials, HIPACT's goal is to provide opportunities for junior faculty of the John A. Burns School of Medicine (JABSOM), University of Hawai'i at Manoa, to acquire knowledge about and to develop skills in clinical trials. HIPACT's partners include the Hawai'i Pacific Health with Kapi'olani Medical Center for Women and Children, and Waianae Coast Comprehensive Health Center. HIPACT builds on the experiences gained through partnerships with the Mountain West IDeA Clinical and Translational Research-Infrastructure Network, and Research Centers in Minority Institutions Translational Research Network. Apart from participating in ECHO ISPCTN-sponsored studies, HIPACT junior faculty serve as committee members, Working Group leaders, Protocol Study Principal Investigators (PI) and site study PIs with ECHO ISPCTN. Through participation in ECHO ISPCTN, HIPACT has successfully increased the number of pediatric and maternal-fetal medicine faculty involved in the conduct of clinical trials.
作为环境对儿童健康结果影响（ECHO）IDea 州儿科临床研究网络（ISPCTN）的 17 个临床站点之一，夏威夷儿科和青少年临床研究 IDeA 中心（HIPACT）于 2016 年成立，旨在参与社区重视和科学有效的多中心儿科临床试验，以改善夏威夷多元化多民族人群的健康和福祉。夏威夷是多种族和服务不足人群的聚居地，包括本土夏威夷社区以及太平洋岛民和亚裔移民人口。这些社区中的许多人都面临着严重的健康差距问题，其地理位置偏远和许多社会经济因素使情况更加恶化。除了为儿童及其家庭提供参与临床试验的机会外，HIPACT 的目标还在于为夏威夷马诺阿大学约翰 A. 伯恩斯医学院（JABSOM）的初级教员提供获取临床试验知识和发展技能的机会。HIPACT 的合作伙伴包括夏威夷太平洋健康公司（与卡皮欧拉尼医疗中心妇女和儿童科合作）和怀阿奈海岸综合健康中心。HIPACT 建立在与山地西部 IDeA 临床和转化研究基础设施网络以及少数民族机构转化研究网络的合作经验之上。除了参与 ECHO ISPCTN 赞助的研究外，HIPACT 的初级教员还担任委员会成员、工作组负责人、方案研究主要研究者（PI）和 ECHO ISPCTN 的站点研究 PI。通过参与 ECHO ISPCTN，HIPACT 成功增加了参与临床试验的儿科和母婴医学教员人数。
