Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Department of Urology, Peking University People's Hospital, Beijing, China.
J Int Med Res. 2020 Jun;48(6):300060520925654. doi: 10.1177/0300060520925654.
To compare body mass index (BMI); serum parameters; and urine parameters between patients with and without urolithiasis.
Data from 1164 patients admitted to our Department of Urology from January 2011 to July 2013 were retrospectively reviewed; 714 patients (age, 5-87 years; male:female ratio, 1.8:1) exhibited urolithiasis, and 450 patients (age, 12-94 years; male:female ratio, 3.8:1) did not. Blood and urine were collected from patients the morning after hospital admission. Serum and urine parameters were checked by an automatic biochemistry analyzer. Statistical analysis included the Mann-Whitney U test and binary logistic regression.
Serum sodium, potassium, chloride, calcium, phosphorus, and carbon dioxide combining power significantly differed between groups. In male patients, serum sodium, calcium, and phosphorus levels were higher in the urolithiasis group, whereas serum potassium and urine pH levels were lower. In female patients, serum sodium was higher in the urolithiasis group. BMI was higher in the urolithiasis group in all patients, male and female. Respective β-values of serum sodium and BMI in male patients were 0.077 and 0.084; in female patients, these values were 0.119 and 0.102.
Changes in serum sodium and BMI may be involved in the pathogenesis and treatment of urolithiasis.
比较有和无尿路结石患者的体重指数（BMI）、血清参数和尿液参数。
回顾性分析 2011 年 1 月至 2013 年 7 月我院泌尿外科收治的 1164 例患者的数据；714 例（年龄 5-87 岁；男：女比例 1.8:1）患有尿路结石，450 例（年龄 12-94 岁；男：女比例 3.8:1）无尿路结石。患者入院次日清晨采集血液和尿液。采用自动生化分析仪检测血清和尿液参数。统计分析包括 Mann-Whitney U 检验和二项逻辑回归。
两组间血清钠、钾、氯、钙、磷和二氧化碳结合力差异有统计学意义。男性患者中，尿路结石组血清钠、钙、磷水平较高，而血清钾和尿 pH 值较低。女性患者中，尿路结石组血清钠较高。所有患者、男性和女性尿路结石组的 BMI 均较高。男性患者血清钠和 BMI 的β值分别为 0.077 和 0.084；女性患者血清钠和 BMI 的β值分别为 0.119 和 0.102。
血清钠和 BMI 的变化可能参与尿路结石的发病机制和治疗。
