COVID-19 患者的脂肪酶升高。
Lipase Elevation in Patients With COVID-19.
机构信息
Division of Gastroenterology, Hepatology, and Endoscopy, Center for Pancreatic Disease, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.
出版信息
Am J Gastroenterol. 2020 Aug;115(8):1286-1288. doi: 10.14309/ajg.0000000000000732.
INTRODUCTION
Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19.
METHODS
A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19.
RESULTS
Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms.
DISCUSSION
Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.
简介
虽然冠状病毒病（COVID-19）与胃肠道表现有关，但它对胰腺的影响尚不清楚。我们旨在评估 COVID-19 患者中高脂血症的频率和特征。
方法
对 6 个美国中心的 COVID-19 住院患者进行回顾性队列研究。
结果
71 例患者中，9 例（12.1%）发生高脂血症，2 例（2.8%）高于正常上限 3 倍。没有患者发生急性胰腺炎。高脂血症与不良结局或症状无关。
讨论
尽管在一些 COVID-19 患者中观察到血清脂肪酶轻度升高，但并未出现临床急性胰腺炎。
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