From the Department of Anaesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India.
Department of Internal Medicine, Westchester Medical Center, Valhalla, New York.
A A Pract. 2020 Jun;14(8):e01230. doi: 10.1213/XAA.0000000000001230.
Gayet-Wernicke encephalopathy (WE) is an acute neurological disorder resulting from deficiency of thiamine, commonly related to chronic abuse of alcohol, but frequently missed or overlooked as a diagnosis when a nonalcoholic patient presents with atypical signs and symptoms of the disease. The diagnosis of the disease is clinical, and confirmation is done by magnetic resonance imaging. We aim to highlight a case of WE in a nonalcoholic postoperative surgical patient receiving total parental nutrition where high-dose intravenous administration of thiamine in time mitigated the symptoms of disease and prevented permanent neurological sequelae. We spotlight the significance of adequate thiamine for postoperative malnourished surgical patients.
Gayet-Wernicke 脑病（WE）是一种由硫胺素缺乏引起的急性神经障碍，通常与慢性酗酒有关，但当非酒精患者出现疾病的非典型体征和症状时，该诊断经常被遗漏或忽视。该疾病的诊断是临床诊断，通过磁共振成像确认。我们旨在强调一例非酒精性术后手术患者在接受全胃肠外营养时出现 WE 的病例，及时给予大剂量静脉注射硫胺素缓解了疾病症状并防止了永久性神经后遗症。我们强调了术后营养不良手术患者充足硫胺素的重要性。
