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长期肠外营养喂养后出现韦尼克脑病

Wernicke's Encephalopathy After Longterm Feeding with Parenteral Nutrition.

作者信息

Akçaboy Zeynep Nur, Yağmurdur Hatice, Baldemir Ramazan, Mutlu Nevzat Mehmet, Dikmen Bayezit

机构信息

Anaesthesiology and Reanimation Department C3 Intensive Care Unit, Ankara Numune Training and Research Hospital, Ankara, Turkey.

出版信息

Turk J Anaesthesiol Reanim. 2014 Apr;42(2):96-9. doi: 10.5152/TJAR.2014.93695. Epub 2014 Jan 6.

DOI:10.5152/TJAR.2014.93695
PMID:27366398
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4894166/
Abstract

Wernicke's encephalopathy occurs due to thiamine (vitamin B1) deficiency which is characterized by occulomotor dysfunction, confusion and ataxia. Although it is most common with alcoholism, can also be seen due to hyperemesis caused by chemotherapy, Crohn's disease, gastrointestinal system surgery, AIDS, bariatric surgery and longterm feeding with parenteral nutrition. In this case, a 51-year-old woman who was treated with longterm total parenteral nutrition due to hyperemesis and had the diagnosis of Wernicke's encephalopathy after admission to the intensive care unit is presented.

摘要

韦尼克脑病是由于硫胺素（维生素B1）缺乏引起的，其特征为动眼神经功能障碍、意识模糊和共济失调。虽然它在酒精中毒患者中最为常见，但在化疗引起的剧烈呕吐、克罗恩病、胃肠道手术、艾滋病、减肥手术以及长期肠外营养喂养等情况下也可能出现。本文介绍了一名51岁女性患者，因剧烈呕吐接受长期全肠外营养治疗，入住重症监护病房后被诊断为韦尼克脑病。

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Total parenteral nutrition-induced Wernicke's encephalopathy after oncologic gastrointestinal surgery.肿瘤胃肠手术后全胃肠外营养诱发的韦尼克脑病
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A Case Report of Nonalcoholic Gayet-Wernicke Encephalopathy: Don't Miss Thiamine.非酒精性 Gayet-Wernicke 脑病 1 例报告：别忽略硫胺素。
A A Pract. 2020 Jun;14(8):e01230. doi: 10.1213/XAA.0000000000001230.

本文引用的文献

1
Wernicke's encephalopathy induced by total parental nutrition.全胃肠外营养所致韦尼克脑病
Nutr Hosp. 2010 Nov-Dec;25(6):1034-6.
2
Neuroimaging findings in acute Wernicke's encephalopathy: review of the literature.急性韦尼克脑病的神经影像学表现：文献综述
AJR Am J Roentgenol. 2009 Feb;192(2):501-8. doi: 10.2214/AJR.07.3959.
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Sudden bilateral blindness in Wernicke's encephalopathy: case report and review of the literature.韦尼克脑病所致突发双侧失明：病例报告及文献综述
J Neurol Sci. 2007 Sep 15;260(1-2):261-4. doi: 10.1016/j.jns.2007.04.005. Epub 2007 May 18.
4
Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management.韦尼克脑病：新的临床情况及诊断与治疗的最新进展
Lancet Neurol. 2007 May;6(5):442-55. doi: 10.1016/S1474-4422(07)70104-7.
5
A case report of Wernicke's encephalopathy in a pediatric patient with anorexia nervosa--restricting type.一例神经性厌食症（限制型）患儿发生韦尼克脑病的病例报告
J Adolesc Health. 2007 Apr;40(4):376-83. doi: 10.1016/j.jadohealth.2006.11.140. Epub 2007 Feb 5.
6
Neurological complications of prolonged hunger strike.长期绝食的神经并发症。
Eur J Neurol. 2006 Oct;13(10):1089-97. doi: 10.1111/j.1468-1331.2006.01531.x.
7
Thiamine (vitamin B1) deficiency and associated brain damage is still common throughout the world and prevention is simple and safe!硫胺素（维生素B1）缺乏及相关脑损伤在全球仍很常见，而预防措施简单又安全！
Eur J Neurol. 2006 Oct;13(10):1078-82. doi: 10.1111/j.1468-1331.2006.01530.x.
8
Hyperemesis gravidarum complicated by Wernicke encephalopathy: background, case report, and review of the literature.妊娠剧吐合并韦尼克脑病：背景、病例报告及文献综述
Obstet Gynecol Surv. 2006 Apr;61(4):255-68. doi: 10.1097/01.ogx.0000206336.08794.65.
9
Nonalcoholic Wernicke's encephalopathy with prominent astasia and optic neuropathy.伴有明显起立不能和视神经病变的非酒精性韦尼克脑病
Med Princ Pract. 2005 Nov-Dec;14(6):438-40. doi: 10.1159/000088119.
10
MR Imaging of nonalcoholic Wernicke encephalopathy: a follow-up study.非酒精性韦尼克脑病的磁共振成像：一项随访研究。
AJNR Am J Neuroradiol. 2005 Oct;26(9):2301-5.

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