睡眠不佳预示着血管变硬。
Broken sleep predicts hardened blood vessels.
机构信息
Center for Human Sleep Science, Department of Psychology, University of California, Berkeley, California, United States of America.
Department of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
出版信息
PLoS Biol. 2020 Jun 4;18(6):e3000726. doi: 10.1371/journal.pbio.3000726. eCollection 2020 Jun.
Why does poor-quality sleep lead to atherosclerosis? In a diverse sample of over 1,600 individuals, we describe a pathway wherein sleep fragmentation raises inflammatory-related white blood cell counts (neutrophils and monocytes), thereby increasing atherosclerosis severity, even when other common risk factors have been accounted for. Improving sleep quality may thus represent one preventive strategy for lowering inflammatory status and thus atherosclerosis risk, reinforcing public health policies focused on sleep health.
为什么睡眠质量差会导致动脉粥样硬化？在一个由 1600 多人组成的多样化样本中，我们描述了这样一种途径：睡眠碎片化会导致与炎症相关的白细胞计数（中性粒细胞和单核细胞）升高，从而增加动脉粥样硬化的严重程度，即使其他常见的风险因素已经被考虑在内。因此，改善睡眠质量可能是降低炎症状态和动脉粥样硬化风险的一种预防策略，这也强化了以睡眠健康为重点的公共卫生政策。
Zotero 插件