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多囊卵巢综合征(PCOS)与青春期:我们该如何应对?

Polycystic ovary syndrome (PCOS) and adolescence: How can we manage it?

作者信息

Capozzi A, Scambia G, Lello S

机构信息

Department of Woman and Child Health, Policlinico Gemelli Foundation- IRCCS Rome, Italy.

Department of Woman and Child Health, Policlinico Gemelli Foundation- IRCCS Rome, Italy.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2020 Jul;250:235-240. doi: 10.1016/j.ejogrb.2020.04.024. Epub 2020 Apr 15.

Abstract

Polycystic Ovary Syndrome is a very complex syndrome, with typical hormonal and metabolic features. In adolescent girls, this condition shows particular characteristics which are in common with adult sign and symptoms, often making the diagnosis difficult. On the other side, treatment strategy aims to manage the different aspects of this syndrome, and is generally based on lifestyle/diet modifications possibly associated with use of estroprogestins, anti-androgens and insulin-sensitizing agents. In this article, we will briefly review both diagnosis and clinical approach to polycystic ovary syndrome in adolescence which still remain a matter of debate in view of the peculiar hormonal milieu of that critical period.

摘要

多囊卵巢综合征是一种非常复杂的综合征,具有典型的激素和代谢特征。在青春期女孩中,这种病症表现出与成人症状相同的特殊特征,常常使诊断变得困难。另一方面,治疗策略旨在应对该综合征的不同方面,通常基于生活方式/饮食调整,可能还会使用雌激素孕激素、抗雄激素和胰岛素增敏剂。在本文中,我们将简要回顾青春期多囊卵巢综合征的诊断和临床处理方法,鉴于该关键时期特殊的激素环境,这些问题仍存在争议。

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