Li Kunpeng, Feng Hongyong, Luo Dawei, Zhang Wen, Yang Keshi, Ji Changbin, Liu Jinlong, Xu Hui
Department of Orthopaedics.
Department of Ultrasonography, Liaocheng People's Hospital, Liaocheng, Shandong, China.
Medicine (Baltimore). 2020 Jun 5;99(23):e20515. doi: 10.1097/MD.0000000000020515.
To evaluate the efficacy and safety of high viscosity bone cement in the percutaneous vertebroplasty (PVP) for treatment of single-level osteoporotic vertebral compression fractures.Eighty patients were enrolled in this study. All patients were received PVP, and they were divided into 2 groups according to the viscosity of bone cement, either high viscosity bone cement (HV group) or low viscosity cement (LV group). Oswestry Disability Index questionnaire and visual analog scale as clinical assessments were quantified. The operative time and injected bone cement volume were recorded. The anterior vertebral height (AVH) and bone cement leakage were evaluated in the radiograph.No significant difference was observed in the operative time. Both groups showed significant improvements in pain relief and functional capacity status (visual analog scale and Oswestry disability index scores) after surgery. Less bone cement volume was injected into the the injured vertebra in the HV group and statistical significance was found between both groups. In the HV group, there was lower leakage rate and less patients of severe leakage compared with the LV group. However, the correction of AVH showed no significant differences between the 2 groups and no significant loss of AVH was observed in 2 groups.High-viscosity and low-viscosity PVP have the similar effects in improving quality of life and relieving pain. There were lower cement leakage rate and less patients of severe leakage in the PVP with high-viscosity bone cement.
评估高粘度骨水泥在经皮椎体成形术（PVP）治疗单节段骨质疏松性椎体压缩骨折中的疗效和安全性。本研究纳入80例患者。所有患者均接受PVP治疗，并根据骨水泥粘度分为2组，即高粘度骨水泥组（HV组）和低粘度骨水泥组（LV组）。采用Oswestry功能障碍指数问卷和视觉模拟量表进行临床评估并量化。记录手术时间和注入的骨水泥量。在X线片上评估椎体前缘高度（AVH）和骨水泥渗漏情况。手术时间差异无统计学意义。两组术后疼痛缓解和功能状态（视觉模拟量表和Oswestry功能障碍指数评分）均有显著改善。HV组注入伤椎的骨水泥量较少，两组间差异有统计学意义。与LV组相比，HV组骨水泥渗漏率较低，严重渗漏的患者较少。然而，两组间AVH的矫正情况差异无统计学意义，且两组均未观察到AVH明显丢失。高粘度和低粘度PVP在改善生活质量和缓解疼痛方面效果相似。使用高粘度骨水泥的PVP骨水泥渗漏率较低，严重渗漏的患者较少。
