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0.35T磁场对EBT3和EBT-XD放射变色薄膜响应的影响。

Influence of 0.35 T magnetic field on the response of EBT3 and EBT-XD radiochromic films.

作者信息

Darafsheh Arash, Hao Yao, Maraghechi Borna, Cammin Jochen, Reynoso Francisco J, Khan Rao

机构信息

Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

出版信息

Med Phys. 2020 Sep;47(9):4543-4552. doi: 10.1002/mp.14313. Epub 2020 Jul 13.

Abstract

PURPOSE

To investigate the inconsistency of recent literature on the effect of magnetic field on the response of radiochromic films, we studied the influence of 0.35 T magnetic field on dosimetric response of EBT3 and EBT-XD Gafchromic films.

METHODS

Two different models of radiochromic films, EBT3 and EBT-XD, were investigated. Pieces of films samples from two different batches for each model were irradiated at different dose levels ranging from 1 to 20 Gy using 6 MV flattening filter free (FFF) x-rays generated by a clinical MR-guided radiotherapy system (B = 0.35 T). Film samples from the same batch were irradiated at corresponding dose levels using 6 MV FFF beam from a conventional linac (B = 0) for comparison. The net optical density was measured 48 h postirradiation using a flatbed scanner. The absorbance spectra were also measured over 500-700 nm wavelength range using a fiber-coupled spectrometer with 2.5 nm resolution. To study the effect of fractionated dose delivery to EBT3 (/EBT-XD) films, 8 (/16) Gy dose was delivered in four 2 (/4) Gy fractions with 24 h interval between fractions.

RESULTS

No significant difference was found in the net optical density and net absorbance of the films irradiated with or without the presence of magnetic field. No dependency on the orientation of the film during irradiation with respect to the magnetic field was observed. The fractionated dose delivery resulted in the same optical density as delivering the whole dose in a single fraction.

CONCLUSIONS

The 0.35 T magnetic field employed in the ViewRay MR-guided radiotherapy system did not show any significant influence on the response of EBT3 and EBT-XD Gafchromic films.

摘要

目的

为了研究近期文献中关于磁场对放射变色薄膜响应影响的不一致性,我们研究了0.35 T磁场对EBT3和EBT-XD放射变色薄膜剂量响应的影响。

方法

研究了两种不同型号的放射变色薄膜EBT3和EBT-XD。使用临床MR引导放射治疗系统(B = 0.35 T)产生的6 MV无均整器(FFF)X射线,对每个型号的两个不同批次的薄膜样本在1至20 Gy的不同剂量水平下进行照射。使用常规直线加速器的6 MV FFF束(B = 0)在相应剂量水平下对同一批次的薄膜样本进行照射以作比较。照射后48小时使用平板扫描仪测量净光密度。还使用分辨率为2.5 nm的光纤耦合光谱仪在500 - 700 nm波长范围内测量吸收光谱。为了研究分次剂量照射对EBT3(/EBT-XD)薄膜的影响,以四个2(/4)Gy分次给予8(/16)Gy剂量,分次之间间隔24小时。

结果

在有或没有磁场存在的情况下照射的薄膜,其净光密度和净吸光度均未发现显著差异。未观察到薄膜在照射期间相对于磁场的取向依赖性。分次剂量照射产生的光密度与单次给予全剂量相同。

结论

ViewRay MR引导放射治疗系统中使用的0.35 T磁场对EBT3和EBT-XD放射变色薄膜的响应未显示出任何显著影响。

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