Division of Medical Radiation Physics, Department of Radiotherapy, Medical University of Vienna, Vienna, Austria. Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Vienna, Austria. Division of Radiation Therapy, Faculty of Medicine Ramathibodi Hospital, Department of Diagnostic and Therapeutic Radiology, Mahidol University, Bangkok, Thailand.
Phys Med Biol. 2018 Mar 15;63(6):065007. doi: 10.1088/1361-6560/aab1ee.
Recently, a new type of radiochromic film, the EBT-XD film, has been introduced for high dose radiotherapy. The EBT-XD film contains the same structure as the EBT3 film but has a slightly different composition and a thinner active layer. This study benchmarks the EBT-XD against EBT3 film for 6 MV and 10 MV photon beams, as well as for 97.4 MeV and 148.2 MeV proton beams and 15-100 kV x-rays. Dosimetric and film reading characteristics, such as post irradiation darkening, film orientation effect, lateral response artifact (LRA), film sensitivity, energy and beam quality dependency were investigated. Furthermore, quenching effects in the Bragg peak were investigated for a single proton beam energy for both film types, in addition measurements were performed in a spread-out Bragg peak. EBT-XD films showed the same characteristic on film darkening as EBT3. The effects between portrait and landscape orientation were reduced by 3.1% (in pixel value) for EBT-XD compared to EBT3 at a dose of 2000 cGy. The LRA is reduced for EBT-XD films for all investigated dose ranges. The sensitivity of EBT-XD films is superior to EBT3 for doses higher than 500 cGy. In addition, EBT-XD showed a similar dosimetric response for photon and proton irradiation with low energy and beam quality dependency. A quenching effect of 10% was found for both film types. The slight decrease in the thickness of the active layer and different composition configuration of EBT-XD resulted in a reduced film orientation effect and LRA, as well as a sensitivity increase in high-dose regions for both photon and proton beams. Overall, the EBT-XD film improved regarding film reading characteristics and showed advantages in the high-dose region for photon and proton beams.
最近,一种新型的放射光致变色胶片 EBT-XD 已被引入用于高剂量放疗。EBT-XD 胶片与 EBT3 胶片具有相同的结构,但组成略有不同,活性层更薄。本研究对 EBT-XD 与 EBT3 胶片在 6MV 和 10MV 光子束以及 97.4MeV 和 148.2MeV 质子束以及 15-100kVx 射线的性能进行了基准测试。本研究考察了剂量学和胶片读取特性,如辐照后黑化、胶片方位效应、侧向响应伪影(LRA)、胶片灵敏度、能量和射束质量依赖性。此外,还研究了两种胶片类型在布拉格峰处的猝灭效应,此外还在展宽布拉格峰处进行了测量。EBT-XD 胶片表现出与 EBT3 胶片相同的黑化特性。与 EBT3 相比,EBT-XD 在 2000cGy 剂量下,胶片方位效应的降低幅度为 3.1%(以像素值计)。对于所有研究的剂量范围,EBT-XD 胶片的 LRA 均有所降低。对于高于 500cGy 的剂量,EBT-XD 胶片的灵敏度优于 EBT3。此外,EBT-XD 胶片对光子和质子照射表现出相似的剂量响应,能量依赖性和射束质量依赖性较低。两种胶片类型都发现了 10%的猝灭效应。EBT-XD 的活性层厚度略有减小,组成结构略有不同,这导致胶片方位效应和 LRA 降低,同时光子和质子射束的高剂量区灵敏度提高。总体而言,EBT-XD 胶片在胶片读取特性方面有所改善,并且在光子和质子射束的高剂量区具有优势。