Bo Kairui, Zhou Zhen, Sun Zhonghua, Gao Yifeng, Zhang Hongkai, Wang Hui, Liu Tong, Xu Lei
Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.
Discipline of Medical Radiation Science, Curtin Medical School, Curtin University, 6845 Perth, Western Australia, Australia.
Rev Cardiovasc Med. 2022 Dec 12;23(12):406. doi: 10.31083/j.rcm2312406. eCollection 2022 Dec.
To evaluate the prognostic value of cardiac magnetic resonance (CMR) imaging in assessing right ventricular strain via meta-analysis of current literature.
Right ventricular strain recorded with CMR serves as a novel indicator to quantify myocardial deformation. Although several studies have reported the predictive value of right ventricular strain determined using CMR, their validity is limited by small sample size and low event number.
Embase, Medline and Web of Science were searched for studies assessing the prognostic value of myocardial strain. The primary endpoint was a composite of all-cause mortality, cardiovascular death, aborted sudden cardiac death, heart transplantation and heart failure admissions.
A total of 14 studies met the selection criteria and were included in the analysis (n = 3239 adults). The random-effects model showed the association of parameters of right ventricular strain with major adverse cardiac events. Absolute value of right ventricular global longitudinal strain was negatively correlated with right ventricular ejection fraction (hazard ratio: 1.07, 95% confidence interval: 1.05-1.08; = 0.013). Despite the small number of studies, right ventricular radial strain, right ventricular circumferential strain and right ventricular long-axis strain displayed potential prognostic value.
Right ventricular strain measured with CMR is an effective prognostic indicator for cardiovascular disease.
通过对现有文献的荟萃分析，评估心脏磁共振成像（CMR）在评估右心室应变方面的预后价值。
CMR记录的右心室应变是量化心肌变形的新指标。尽管有几项研究报告了使用CMR测定的右心室应变的预测价值，但它们的有效性受到样本量小和事件数量少的限制。
检索Embase、Medline和Web of Science数据库，查找评估心肌应变预后价值的研究。主要终点是全因死亡、心血管死亡、心脏性猝死未遂、心脏移植和心力衰竭入院的综合指标。
共有14项研究符合入选标准并纳入分析（n = 3239名成年人）。随机效应模型显示右心室应变参数与主要不良心脏事件之间的关联。右心室整体纵向应变的绝对值与右心室射血分数呈负相关（风险比：1.07，95%置信区间：1.05 - 1.08；P = 0.013）。尽管研究数量较少，但右心室径向应变、右心室圆周应变和右心室长轴应变显示出潜在的预后价值。
CMR测量的右心室应变是心血管疾病的有效预后指标。
