Department of Psychiatry, Saint-Luc University Hospital and Institute of Neuroscience (IoNS), Université catholique de Louvain, 10 Avenue Hippocrate, B-1200 Brussels, Belgium; Department of Psychiatry, University of Kinshasa, Lemba, Kinshasa, Democratic Republic of Congo.
Laboratory for Experimental Psychopathology, Psychological Sciences Research Institute, Université Catholique de Louvain, 10 Place C. Mercier, B-1348 Louvain-la-Neuve, Belgium.
Psychiatry Res. 2020 Aug;290:112951. doi: 10.1016/j.psychres.2020.112951. Epub 2020 May 15.
Deficits in social perception and knowledge and their negative impact on social functioning, have been repeatedly reported among patients with schizophrenia. However, earlier studies have focused on an overall assessment of social perception and social knowledge, without exploring their sub-components nor the interindividual variation of the deficit. This study aims to refine the exploration of this deficit and to assess its interindividual variation. Twenty-nine patients with schizophrenia and 24 healthy controls, matched for age and gender, completed a validated and integrated social perception and knowledge task (i.e. the PerSo test). Patients with schizophrenia had reduced performance in all PerSo subtests, namely contextual fluency, interpretation and social convention. However, these deficits were not correlated with the severity of clinical symptoms, and individual profiles analyses showed a marked heterogeneity among patients on their abilities. Our study confirms the existence of deficits in social perception and knowledge and underlines their considerable heterogeneity. Therefore, it is necessary to test and rehabilitate individually social perception and knowledge.
社会知觉和知识缺陷及其对社会功能的负面影响在精神分裂症患者中反复被报道。然而，早期的研究主要集中在对社会知觉和社会知识的整体评估上，而没有探讨其亚成分，也没有探讨缺陷的个体间变异。本研究旨在进一步探索这一缺陷，并评估其个体间的变异。29 名精神分裂症患者和 24 名年龄和性别相匹配的健康对照者完成了一项经过验证和整合的社会知觉和知识任务（即 PerSo 测试）。精神分裂症患者在所有 PerSo 子测试中的表现都较差，即语境流畅性、解释和社会习俗。然而，这些缺陷与临床症状的严重程度无关，个体特征分析显示患者在能力上存在明显的异质性。我们的研究证实了社会知觉和知识缺陷的存在，并强调了它们的巨大异质性。因此，有必要对社会知觉和知识进行个体化的测试和康复。
