Tianjin Key Laboratory of Food Science and Health, School of Medicine, Nankai University, Tianjin, 300071, China.
Beijing San Yuan Foods Co., Ltd., No. 8, Yingchang Road, Yinghai, Daxing District, Beijing, 100076, China.
J Food Sci. 2020 Jul;85(7):2105-2113. doi: 10.1111/1750-3841.15181. Epub 2020 Jun 7.
As a kind of polymer material additive, phthalic acid esters (PAEs) are widely used in food industry. However, PAEs are environmental endocrine disruptors with reproductive toxicity and teratogenic carcinogenicity, which are difficult to be degraded in the natural environment. In this paper, gas chromatography-mass spectrometer (GC-MS) methods for PAEs in polyethylene wrap film were optimized. For diisobutyl phthalate (DIBP) and dibutyl phthalate (DBP) that were mainly detected, the method had a good linearity in 1 to 500 ng/g. Then, we confirmed that the migration of DIBP and DBP from polyethylene wrap film increased with time and temperature. It is found that the migration law in different food simulations well followed the migration dynamics first-level model. The rate constant K and initial release rate V are inversely proportional to the polarity of the simulated liquid. We hope that this study can serve as a valuable reference for further research on the migration of food packing materials. PRACTICAL APPLICATION: In this paper, we present a simple example of applying migration model to evaluate the migration behaviors of PAEs in food packaging materials along with their hazardous properties. It can serve as a valuable reference for further research on the migration of food packing materials.
作为一种聚合物材料添加剂，邻苯二甲酸酯（PAEs）广泛应用于食品工业。然而，PAEs 是环境内分泌干扰物，具有生殖毒性和致畸致癌性，在自然环境中难以降解。本文优化了气相色谱-质谱联用（GC-MS）法测定聚乙烯包装膜中 PAEs 的含量。对于主要检测到的邻苯二甲酸二异丁酯（DIBP）和邻苯二甲酸二丁酯（DBP），该方法在 1 至 500ng/g 范围内具有良好的线性关系。然后，我们证实了 DIBP 和 DBP 从聚乙烯包装膜中的迁移量随时间和温度的增加而增加。研究发现，不同食品模拟物中的迁移规律很好地遵循了迁移动力学一级模型。速率常数 K 和初始释放率 V 与模拟液的极性成反比。我们希望本研究能为进一步研究食品包装材料的迁移规律提供有价值的参考。实际应用：本文通过一个简单的例子，应用迁移模型评估了食品包装材料中 PAEs 的迁移行为及其危害性。它可以为进一步研究食品包装材料的迁移提供有价值的参考。
