Shandong Provincial Key Laboratory of Molecular Engineering, School of Chemistry and Pharmaceutical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, People's Republic of China.
Shandong Provincial Key Laboratory of Molecular Engineering, School of Chemistry and Pharmaceutical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, People's Republic of China.
Anal Chim Acta. 2020 Aug 1;1123:64-72. doi: 10.1016/j.aca.2020.04.079. Epub 2020 May 13.
A new oligothiophene derivative (3TY) was synthesized, and used as a highly selective hydrazine (NH) chemosensor in ∼100% aqueous solution with "naked-eye" colorimetric and "turn-on" fluorimetric response. This chemosensor 3TY enabled ultrafast and ultrasensitive detection of hydrazine with ultralow detection limit of 1.45 nM (0.04 ppb) in a wide sensing pH range from 6 to 10. The sensing mechanism of 3TY toward hydrazine was strongly and fully confirmed. More importantly, colorimetric paper test strip and solid support silica are easily prepared by 3TY for on-site and real-time detection of hydrazine. Furthermore, 3TY displays many potential applications for detecting NH in environmental water and human urine along with bio-imaging in living HeLa cells.
合成了一种新的寡噻吩衍生物（3TY），并将其用作在约 100%水溶液中具有“肉眼可见”比色和“开启”荧光响应的高选择性肼（NH）化学传感器。这种化学传感器 3TY 能够超快速和超灵敏地检测肼，在检测 pH 值范围从 6 到 10 的宽范围内，检测限低至 1.45 nM（0.04 ppb）。3TY 对肼的传感机制得到了强有力和充分的证实。更重要的是，3TY 很容易制备比色试纸条和固体支撑硅胶，可用于现场和实时检测肼。此外，3TY 还可用于检测环境水和人尿中的 NH 以及在活 HeLa 细胞中进行生物成像等多个潜在应用。
