Sharini H, Riyahi Alam N, Khabiri H, Arabalibeik H, Hashemi H, Azimi A R, Masjoodi S
Department of Biomedical Engineering, Faculty of Medicine, Kermanshah University of Medical Sciences (KUMS), Kermanshah, Iran.
Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran; PERFORM Center, Concordia University, Montreal, QC, Canada; Pharmaceutical Sciences Research Center (PSRC), The institute of Pharmaceutical Sciences, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Med Eng Phys. 2020 Sep;83:112-122. doi: 10.1016/j.medengphy.2020.05.008. Epub 2020 May 17.
Magnetic Resonance Imaging (MRI) can be applied to study the effects of rehabilitation strategies for neuroscience research. An MRI-wrist robot is designed and used as a clinical tool to examine the process of the brain plasticity changes. In this robot, the patient actuation is accomplished with two standard air cylinders, located inside the MRI chamber with two degrees of freedom (flexion-extension and ulna-radial deviation) with pneumatic air transmission, consisting of simple mechanism converting rotary motion to linear independently. A pilot study of brain image aiming at revealing more effective therapeutic strategies carried out to confirm the technical aspects of the development and validation. In a healthy subject, both wrist movement of robot and subject demonstrated brain activity in the contralateral primary somatosensory cortex. Because the robot does not move during the patient's body, a stand was designed to allow the wrist robot and patient to fit comfortably within the MRI machine. While all the parts of the robot were carefully selected with strict MRI compatibility requirements, the robot was tested by presenting some pilot imaging data with null effects on the image quality, as well. Finally, the possible further development of the robot has been introduced for a rehabilitation assessment.
磁共振成像（MRI）可用于研究康复策略对神经科学研究的影响。设计了一种MRI手腕机器人，并将其用作临床工具来检查大脑可塑性变化的过程。在这个机器人中，患者的驱动由两个标准气缸完成，这两个气缸位于MRI腔室内，具有两个自由度（屈伸和尺桡偏斜），通过气动空气传输实现，由简单的机构独立地将旋转运动转换为直线运动。针对揭示更有效的治疗策略进行了一项脑成像初步研究，以确认开发和验证的技术方面。在一名健康受试者中，机器人和受试者的手腕运动均在对侧初级体感皮层显示出大脑活动。由于机器人在患者身体运动时不移动，因此设计了一个支架，以使手腕机器人和患者能够舒适地适配在MRI机器内。虽然机器人的所有部件都根据严格的MRI兼容性要求进行了精心挑选，但该机器人也通过呈现一些对图像质量无影响的初步成像数据进行了测试。最后，介绍了该机器人在康复评估方面可能的进一步发展。
