Dental Materials Science, Applied Oral Sciences, Faculty of Dentistry, The University of Hong Kong.
Dent Mater J. 2020 Aug 2;39(4):523-530. doi: 10.4012/dmj.2019-200. Epub 2020 Jun 6.
Zirconia (ZrO) ceramic is widely used in dentistry as a clinical dental biomaterial. In this review, we are focusing on and summarizing the biological performance of zirconia under different surface characteristics. We have included an initial tissue cell attachment study on zirconia and bacterial adhesion on zirconia. Our results suggest that surface modifications applied on zirconia may change the interfacial surface characteristics e.g. surface roughness, surface free energy, and chemistry of zirconia. The modifications also result in advanced biological performance of zirconia, including enhanced tissue cell attachment and reduction of bacterial adhesion. The recent laboratory research has provided many interesting modification methods and showed clinically interesting and promising outcomes. A few of the outcomes are validated and have been applied in clinical dentistry.
氧化锆（ZrO）陶瓷作为一种临床牙科生物材料，在牙科领域得到了广泛的应用。在本次综述中，我们主要聚焦并总结了不同表面特性下氧化锆的生物学性能。我们纳入了氧化锆初始组织细胞黏附研究和氧化锆表面细菌黏附研究。结果表明，应用于氧化锆表面的改性处理可以改变界面表面特性，如表面粗糙度、表面自由能和氧化锆化学性质。这些改性处理还可使氧化锆具有更好的生物学性能，包括增强组织细胞黏附、减少细菌黏附。近期的实验室研究提供了许多有趣的改性方法，并显示出了有前景的临床应用结果。其中一些结果已得到验证，并已应用于临床牙科。
