Choksi Dhaval, Kolhe Kailash M, Ingle Meghraj, Rathi Chetan, Khairnar Harshad, Chauhan Shamshersingh G, Chaudhary Vipul, Shukla Akash, Pandey Vikas
Department of Gastroenterology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India.
J Family Med Prim Care. 2020 Mar 26;9(3):1695-1699. doi: 10.4103/jfmpc.jfmpc_1111_19. eCollection 2020 Mar.
Esophageal carcinoma is a common gastrointestinal malignancy. There is a paucity of literature about the time trends from India. The aim of the study was to evaluate the time trends over 20 years and observe how they differ from the West.
We retrospectively evaluated the data of 552 patients from the gastroenterology database (single department, single-center) over a period of 20 years from 1996 to 2015. The study period was split into two groups, namely, Group A (1996 to 2005) and Group B (2006 to 2015).
There were 263 patients in Group A and 289 patients in Group B. The mean age was 54.83 years (range 25-89 years). There were 345 males and 207 females, with the ratio being 1.67. The most common histological type was squamous cell carcinoma (SCC) with 443 patients (80.25%). The most common location was mid esophagus with 229 patients (41.48%) followed by 208 patients (37.68%) in the lower esophagus. There was no significant increase in the lower esophageal malignancy. However, there was a significant increase in the gastroesophageal junction (GEJ) and adenocarcinoma (AC). There were no other time trend changes in gender, location, or histology.
SCC is still far more common than AC in India. The mid esophagus is the most common site. There is no evidence of an increase in the lower esophageal malignancy in our study for over 20 years. However, the rates of GEJ-AC were found to be increasing.
食管癌是一种常见的胃肠道恶性肿瘤。关于印度时间趋势的文献较少。本研究的目的是评估20年期间的时间趋势，并观察其与西方的差异。
我们回顾性评估了1996年至2015年20年间来自胃肠病学数据库（单一科室、单一中心）的552例患者的数据。研究期分为两组，即A组（1996年至2005年）和B组（2006年至2015年）。
A组有263例患者，B组有289例患者。平均年龄为54.83岁（范围25 - 89岁）。男性345例，女性207例，比例为1.67。最常见的组织学类型是鳞状细胞癌（SCC），共443例患者（80.25%）。最常见的部位是食管中段，有229例患者（41.48%），其次是食管下段208例患者（37.68%）。食管下段恶性肿瘤无显著增加。然而，胃食管交界部（GEJ）和腺癌（AC）有显著增加。在性别、部位或组织学方面没有其他时间趋势变化。
在印度，SCC仍然比AC常见得多。食管中段是最常见的部位。在我们超过20年的研究中，没有证据表明食管下段恶性肿瘤有所增加。然而，发现GEJ - AC的发生率在增加。
