Bhome Rohan, Desai Devendra, Abraham Philip, Joshi Anand, Gupta Tarun, Bhaduri Anita, Kapadia Asha, Patel Krishna, Bhome Rahul
Division of Gastroenterology, P D Hinduja National Hospital and Medical Research Centre, Mumbai 400 016, India.
Indian J Gastroenterol. 2012 Dec;31(6):340-2. doi: 10.1007/s12664-012-0250-9. Epub 2012 Sep 16.
There is a paucity of literature from the Indian subcontinent looking at the prevalence of esophageal cancer by histological type. In our study, we ascertained the relative proportion and location of adenocarcinoma (AC) and squamous cell carcinoma (SCC) of the esophagus at a referral hospital in Mumbai, India over a 12-year period to assess whether a time-trend existed. A retrospective analysis was carried out on patients who were diagnosed with and/or treated for esophageal cancer at the P D Hinduja Hospital and Research Centre in Mumbai between January 1, 2000 and December 31, 2011. Data were procured from histopathology and oncology registers of the institute, the database of the Gastroenterology consultants, the Endoscopy Department records and from the Medical Records Department. Of the 445 cases of esophageal cancer with known histology, 104 (23 %) were AC and 314 (71 %) were SCC. Over the 12-year period, the proportions of AC compared to SCC did not show a statistically significant temporal change (p = 0.145). AC comprised nearly a quarter of esophageal carcinoma in Mumbai. There has been no significant change in the number and proportion of AC and SCC in the 12-year period.
来自印度次大陆的关于按组织学类型划分的食管癌患病率的文献较少。在我们的研究中，我们确定了印度孟买一家转诊医院12年间食管腺癌（AC）和鳞状细胞癌（SCC）的相对比例及位置，以评估是否存在时间趋势。对2000年1月1日至2011年12月31日期间在孟买P D Hinduja医院和研究中心被诊断为食管癌和/或接受食管癌治疗的患者进行了回顾性分析。数据来自该研究所的组织病理学和肿瘤学登记册、胃肠病学顾问数据库、内镜科记录以及病历科。在445例已知组织学类型的食管癌病例中，104例（23%）为AC，314例（71%）为SCC。在这12年期间，AC与SCC的比例没有显示出统计学上显著的时间变化（p = 0.145）。在孟买，AC约占食管癌的四分之一。在这12年期间，AC和SCC的数量及比例没有显著变化。
