Department of Dermatology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
Department of Dermatology, Faculty of Medicine, Ahi Evran University, Kırşehir, Turkey.
Clin Dermatol. 2020 Mar-Apr;38(2):160-175. doi: 10.1016/j.clindermatol.2019.10.001. Epub 2019 Oct 24.
HIV is associated with an increased incidence of mucocutaneous disorders, with the overwhelming majority of HIV-infected individuals being afflicted with skin diseases during the course of the infection. Skin diseases in HIV patients are rarely fatal, but they have a significant effect on the quality of life. The immunologic stage of the infection and the use of highly active antiretroviral therapy (HAART) are the main elements that determine the spectrum of the mucocutaneous involvement. Many skin diseases may occur simultaneously in HIV patients, and the course of these diseases may or may not be different than it is in HIV-negative individuals. The unusual, severe, and different presentations of the mucocutaneous involvement make HIV one of the great imitators in dermatology.
HIV 与黏膜皮肤疾病的发病率增加有关,绝大多数 HIV 感染者在感染过程中都会患上皮肤病。HIV 患者的皮肤病很少致命,但对生活质量有重大影响。感染的免疫阶段和使用高效抗逆转录病毒治疗 (HAART) 是决定黏膜皮肤受累范围的主要因素。许多皮肤病可能同时发生在 HIV 患者身上,这些疾病的病程可能与 HIV 阴性个体不同。黏膜皮肤受累的不寻常、严重和不同表现使得 HIV 成为皮肤科的一大模仿者。