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直肠疼痛综合征:诊断与管理的最新进展

Proctalgia Syndromes: Update in Diagnosis and Management.

作者信息

Carrington Emma Victoria, Popa Stefan-Lucian, Chiarioni Giuseppe

机构信息

Department of Colorectal Surgery, St Vincent's University Hospital, University College Dublin, Dublin, Ireland.

2nd Medical Department, "Iuliu Hatieganu", University of Medicine and Pharmacy, Cluj-Napoca, Romania.

出版信息

Curr Gastroenterol Rep. 2020 Jun 9;22(7):35. doi: 10.1007/s11894-020-00768-0.

Abstract

PURPOSE OF REVIEW

Functional anorectal pain syndromes are a neglected yet often disabling clinical entity resulting in significant economic and psychological burden to the patient. The aim of this review is to update the practicing gastroenterologist/coloproctologist on the diagnosis and management of these complicated disorders.

RECENT FINDINGS

The updated Rome foundation diagnostic criteria (Rome IV) for functional anorectal pain subgroups chronic proctalgia (levator ani syndrome and unspecified functional anorectal pain) and acute proctalgia (proctalgia fugax) on the basis of symptom duration and digital rectal examination findings. Chronic proctalgia is thought to be secondary to paradoxical pelvic floor contraction in many patients and biofeedback to improve the defecation effort has proven effective for over 90% in the short term. Unfortunately, management of proctalgia fugax remains challenging and treatment outcomes modest at best. A number of therapies to relax the pelvic floor may be employed to improve symptoms in functional anorectal pain syndromes; however, only biofeedback to improve defaecatory dynamics in patients with levator ani syndrome has proven effectiveness in a randomized setting. Further investigation of treatment approaches in proctalgia fugax is required.

摘要

综述目的

功能性肛门直肠疼痛综合征是一种被忽视但常导致功能障碍的临床病症,给患者带来巨大的经济和心理负担。本综述旨在向执业胃肠病学家/结直肠外科医生介绍这些复杂疾病的诊断和管理方法。

最新发现

罗马基金会根据症状持续时间和直肠指检结果,对功能性肛门直肠疼痛亚组(慢性直肠疼痛,即肛提肌综合征和未特定的功能性肛门直肠疼痛,以及急性直肠疼痛,即直肠痛性痉挛)更新了诊断标准(罗马IV)。许多患者的慢性直肠疼痛被认为继发于盆底反常收缩,短期内,生物反馈疗法改善排便用力的有效率已被证实超过90%。不幸的是,直肠痛性痉挛的管理仍然具有挑战性,治疗效果充其量只能说是一般。可采用多种放松盆底的疗法来改善功能性肛门直肠疼痛综合征的症状;然而,只有改善肛提肌综合征患者排便动力学的生物反馈疗法在随机对照试验中被证实有效。直肠痛性痉挛的治疗方法需要进一步研究。

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