Freedman David S, Goodman Alyson B, King Raymond J, Blanck Heidi M
Division of Nutrition, Physical Activity and Obesity Centers for Disease Control and Prevention Atlanta Georgia.
Obes Sci Pract. 2020 Feb 8;6(3):300-306. doi: 10.1002/osp4.407. eCollection 2020 Jun.
As obesity among children and adolescents is associated with major health risks, including the persistence of obesity into adulthood, there has been interest in targeting prevention efforts at children and adolescent. The longitudinal tracking of BMI and obesity, as well as the effects of initial age and duration of follow-up on this tracking, were examined in a large electronic health record (EHR) database.
The data consisted of 2.04 million children who were examined from 2006 through 2018. These children were initially examined between ages 2 and 9 years and had a final examination, on average, 4 years later.
Overall, children with obesity at one examination were 7.7 times more likely to have obesity at a subsequent examination than children with a BMI ≤ 95 percentile. Further, 71% of children with obesity at one examination continued to have obesity at re-examination. Although 2-year-olds had a relative risk of 5.5 and a positive predictive value of 54%, then sensitivity of obesity at younger ages was low. Of the children who were re-examined after age 10 y and found to have obesity, only 22% had a BMI ≥ 95 percentile at age 2 years.
Despite the tracking of obesity at all ages, these results agree with previous reports that have found that an elevated BMI at a very young age will identify only a small proportion of older children with obesity.
由于儿童和青少年肥胖与重大健康风险相关,包括肥胖持续至成年期,因此人们对针对儿童和青少年开展预防工作很感兴趣。在一个大型电子健康记录(EHR)数据库中,对体重指数(BMI)和肥胖情况进行了纵向追踪,并研究了初始年龄和随访时间对这种追踪的影响。
数据包括2006年至2018年接受检查的204万名儿童。这些儿童最初在2至9岁之间接受检查,平均4年后进行最后一次检查。
总体而言,一次检查时肥胖的儿童在随后检查时患肥胖症的可能性是BMI≤第95百分位数儿童的7.7倍。此外,一次检查时肥胖的儿童中,71%在再次检查时仍患有肥胖症。虽然2岁儿童的相对风险为5.5,阳性预测值为54%,但低龄儿童肥胖的敏感性较低。在10岁后重新接受检查并被发现患有肥胖症的儿童中,只有22%在2岁时BMI≥第95百分位数。
尽管对各年龄段的肥胖情况进行了追踪,但这些结果与之前的报告一致,即非常年幼时BMI升高仅能识别一小部分年龄较大的肥胖儿童。