益生菌和饮食能否促进冠状病毒感染中的有益免疫调节和嘌呤控制？
Can Probiotics and Diet Promote Beneficial Immune Modulation and Purine Control in Coronavirus Infection?
机构信息
Nutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
Biochemistry Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN 59078-970, Brazil.
出版信息
Nutrients. 2020 Jun 10;12(6):1737. doi: 10.3390/nu12061737.
Infection caused by the SARS-CoV-2 coronavirus worldwide has led the World Health Organization to declare a COVID-19 pandemic. Because there is no cure or treatment for this virus, it is emergingly urgent to find effective and validated methods to prevent and treat COVID-19 infection. In this context, alternatives related to nutritional therapy might help to control the infection. This narrative review proposes the importance and role of probiotics and diet as adjunct alternatives among the therapies available for the treatment of this new coronavirus. This review discusses the relationship between intestinal purine metabolism and the use of and low-purine diets, particularly in individuals with hyperuricemia, as adjuvant nutritional therapies to improve the immune system and weaken viral replication, assisting in the treatment of COVID-19. These might be promising alternatives, in addition to many others that involve adequate intake of vitamins, minerals and bioactive compounds from food.
由于新型冠状病毒（SARS-CoV-2）引起的感染，世界卫生组织已宣布 COVID-19 大流行。由于目前尚无针对该病毒的治愈或治疗方法，因此迫切需要寻找有效和经过验证的方法来预防和治疗 COVID-19 感染。在这种情况下，与营养疗法相关的替代方法可能有助于控制感染。本综述性文章提出了益生菌和饮食作为治疗这种新型冠状病毒的可用疗法的辅助替代方法的重要性和作用。本文讨论了肠道嘌呤代谢与使用和低嘌呤饮食之间的关系，特别是在高尿酸血症患者中，作为辅助营养疗法以改善免疫系统和减弱病毒复制，从而辅助 COVID-19 的治疗。除了许多涉及从食物中摄取足够的维生素、矿物质和生物活性化合物的其他方法之外，这些可能是很有前景的替代方法。
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