• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

以海洛因为基础的毒品“伍onga”的起始轨迹——来自南非的定性证据。

Trajectories of initiation for the heroin-based drug whoonga - qualitative evidence from South Africa.

作者信息

Tyree Griffin A, Mosery Nzwakie, Closson Elizabeth F, Mabude Zonke, du Toit Carol, Bangsberg David R, Safren Steven A, Mayer Kenneth H, Smit Jennifer A, Mimiaga Matthew J, Grelotti David J

机构信息

University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, United States.

MatCH Research Unit (MRU), Department of Obstetrics and Gynaegology, Faculty of Health Sciences, University of the Witwatersrand, 40 Dr AB Xuma Street, Suite 1108-9, Commercial City, Durban, KwaZulu-Natal 4001, South Africa.

出版信息

Int J Drug Policy. 2020 Aug;82:102799. doi: 10.1016/j.drugpo.2020.102799. Epub 2020 Jun 12.

DOI:10.1016/j.drugpo.2020.102799
PMID:32535541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7493467/
Abstract

BACKGROUND

Whoonga is a smoked heroin-based street drug that first emerged in South Africa a decade ago. While previous scientific reports suggest that use is growing and youth are particularly vulnerable, trajectories of initiation are not well characterized.

METHODS

In 2015, 30 men undergoing residential addiction treatment for this smoked heroin drug in KwaZulu-Natal, South Africa participated in semi-structured interviews about their experiences using the drug. Interview data were coded using qualitative content analysis.

RESULTS

Participant trajectories to initiating smoked heroin were "vertical" in the context of marijuana use or "horizontal" in the context of other hard drug use. Participants reporting vertical trajectories began smoking heroin as youth at school or in other settings where people were smoking marijuana. Several participants with horizontal trajectories started smoking heroin to address symptoms of other drug or alcohol addiction. Social influences on initiation emerged as an overarching theme. Members of participants' social networks who were smoking or distributing heroin figured prominently in initiation narratives. Surprisingly, references to injection drug use were absent from initiation narratives. Participants reported people who smoke heroin differ from those who inject heroin by race.

CONCLUSION

Consistent with theories implicating social and structural influences on substance use initiation, people who started smoking heroin had social contacts who smoked heroin and frequented places where substance use was common. Smoked heroin initiation for several participants with horizontal trajectories may have been averted if they accessed evidence-based treatments for stimulant or alcohol use disorders. With increasing reports of heroin use across Africa, a coordinated approach to address this growing epidemic is needed. However, because smoked heroin and injection heroin use occur in distinct risk environments, interventions tailored to people who use smoked heroin will be needed to prevent smoked heroin use, prevent transition to injection use, and mitigate other social harms.

摘要

背景

“翁加”是一种以烟熏海洛因为基础的街头毒品,十年前首次出现在南非。虽然此前的科学报告表明其使用正在增加,且年轻人尤其易受影响,但起始轨迹尚未得到很好的描述。

方法

2015年,南非夸祖鲁 - 纳塔尔省30名因吸食这种烟熏海洛因而接受住院成瘾治疗的男性参与了关于他们使用该毒品经历的半结构化访谈。访谈数据采用定性内容分析法进行编码。

结果

吸食烟熏海洛因的参与者起始轨迹在吸食大麻的背景下是“纵向的”,在使用其他硬性毒品的背景下是“横向的”。报告纵向轨迹的参与者在青少年时期于学校或其他人吸食大麻的场所开始吸食海洛因。几名有横向轨迹的参与者开始吸食海洛因是为了缓解其他毒品或酒精成瘾的症状。社会对起始的影响成为一个总体主题。参与者社交网络中吸食或分销海洛因的成员在起始叙述中占据显著位置。令人惊讶的是,起始叙述中没有提及注射吸毒。参与者报告称,吸食海洛因的人与注射海洛因的人在种族上有所不同。

结论

与暗示社会和结构因素对物质使用起始有影响的理论一致,开始吸食海洛因的人有吸食海洛因的社会联系人,且常去物质使用普遍的场所。如果几名有横向轨迹的参与者能够获得针对兴奋剂或酒精使用障碍的循证治疗,或许可以避免他们开始吸食烟熏海洛因。随着非洲各地海洛因使用报告的增加,需要采取协调一致的方法来应对这一日益严重的流行病。然而,由于吸食烟熏海洛因和注射海洛因发生在不同的风险环境中,需要针对吸食烟熏海洛因者量身定制干预措施,以预防吸食烟熏海洛因、防止转向注射使用,并减轻其他社会危害。

相似文献

1
Trajectories of initiation for the heroin-based drug whoonga - qualitative evidence from South Africa.以海洛因为基础的毒品“伍onga”的起始轨迹——来自南非的定性证据。
Int J Drug Policy. 2020 Aug;82:102799. doi: 10.1016/j.drugpo.2020.102799. Epub 2020 Jun 12.
2
Risk perception, changing social context, and norms prevent transition to regular injection among people who smoke heroin.风险认知、不断变化的社会环境和规范因素阻碍了吸食海洛因人群向常规注射方式的转变。
Drug Alcohol Depend. 2020 Mar 1;208:107878. doi: 10.1016/j.drugalcdep.2020.107878. Epub 2020 Jan 22.
3
"Every 'never' I ever said came true": transitions from opioid pills to heroin injecting.“我所说的每一个‘绝不’都成真了”:从服用阿片类药丸到注射海洛因的转变
Int J Drug Policy. 2014 Mar;25(2):257-66. doi: 10.1016/j.drugpo.2013.10.004. Epub 2013 Oct 19.
4
Fronto-temporal cortical atrophy in 'nyaope' combination heroin and cannabis use disorder.“ nyaope”组合使用海洛因和大麻导致额颞皮质萎缩。
Drug Alcohol Depend. 2021 Apr 1;221:108630. doi: 10.1016/j.drugalcdep.2021.108630. Epub 2021 Feb 16.
5
A qualitative analysis of transitions to heroin injection in Kenya: implications for HIV prevention and harm reduction.肯尼亚向海洛因注射转变的定性分析:对艾滋病毒预防和减少伤害的启示。
Harm Reduct J. 2015 Sep 4;12:27. doi: 10.1186/s12954-015-0061-2.
6
Post-Vietnam heroin use and injection by returning US veterans: clues to preventing injection today.越战归国美国退伍军人的海洛因使用与注射情况:当今预防注射的线索
Addiction. 2003 Aug;98(8):1053-60. doi: 10.1046/j.1360-0443.2003.00436.x.
7
Whoonga: potential recreational use of HIV antiretroviral medication in South Africa.南非:潜在的 HIV 抗逆转录病毒药物的娱乐性使用
AIDS Behav. 2014 Mar;18(3):511-8. doi: 10.1007/s10461-013-0575-0.
8
Whoonga and the abuse and diversion of antiretrovirals in Soweto, South Africa.南非索韦托的“威刚”和抗逆转录病毒药物的滥用与转移。
AIDS Behav. 2014 Jul;18(7):1378-80. doi: 10.1007/s10461-013-0683-x.
9
[Out of addictions: Alcohol, or alcohol to alcohol].摆脱成瘾:酒精成瘾,或从一种酒精状态到另一种酒精状态
Encephale. 2017 Aug;43(4):326-333. doi: 10.1016/j.encep.2016.02.016. Epub 2016 Jun 29.
10
Initiation into heroin use among street-involved youth in a Canadian setting: A longitudinal cohort study.在加拿大环境下,街头流浪青年开始使用海洛因的情况:一项纵向队列研究。
Drug Alcohol Depend. 2019 Dec 1;205:107579. doi: 10.1016/j.drugalcdep.2019.107579. Epub 2019 Sep 21.

引用本文的文献

1
The Impact of Drugs and Substance Abuse on Viral Pathogenesis-A South African Perspective.毒品和药物滥用对病毒发病机制的影响——南非视角。
Viruses. 2024 Jun 17;16(6):971. doi: 10.3390/v16060971.
2
ART coverage and viral suppression among female sex workers living with HIV in eThekwini, South Africa: Baseline findings from the Siyaphambili study.南非伊泰夸尼地区感染艾滋病毒的女性性工作者的抗逆转录病毒治疗覆盖率和病毒抑制情况:“我们一起前进”研究的基线结果
PLOS Glob Public Health. 2024 May 22;4(5):e0002783. doi: 10.1371/journal.pgph.0002783. eCollection 2024.
3
Polysubstance Use Profiles and HIV Viremia in a South African Cohort of Female Sex Workers: A Latent Class Analysis.南非女性性工作者队列中的多物质使用特征和 HIV 病毒血症:潜在类别分析。
J Acquir Immune Defic Syndr. 2024 Mar 1;95(3):222-230. doi: 10.1097/QAI.0000000000003356.
4
High risk injection drug use and uptake of HIV prevention and treatment services among people who inject drugs in KwaZulu-Natal, South Africa.南非夸祖鲁-纳塔尔省高危注射吸毒者的 HIV 预防和治疗服务的使用率。
PLoS One. 2023 May 12;18(5):e0281030. doi: 10.1371/journal.pone.0281030. eCollection 2023.
5
'Voice needs teeth to have bite'! Expanding community-led multisectoral action-learning to address alcohol and drug abuse in rural South Africa.“发声需要有力度”!扩大由社区主导的多部门行动学习,以解决南非农村地区的酒精和药物滥用问题。
PLOS Glob Public Health. 2022 Oct 19;2(10):e0000323. doi: 10.1371/journal.pgph.0000323. eCollection 2022.
6
High risk injection drug use and uptake of HIV prevention and treatment services among people who inject drugs in KwaZulu-Natal, South Africa.南非夸祖鲁-纳塔尔省注射吸毒者中的高风险注射吸毒行为以及艾滋病毒预防和治疗服务的利用情况
medRxiv. 2023 Jan 18:2023.01.16.23284613. doi: 10.1101/2023.01.16.23284613.
7
A vapor exposure method for delivering heroin alters nociception, body temperature and spontaneous activity in female and male rats.一种用于输送海洛因的蒸汽暴露方法会改变雌性和雄性大鼠的痛觉感受、体温及自发活动。
J Neurosci Methods. 2021 Jan 15;348:108993. doi: 10.1016/j.jneumeth.2020.108993. Epub 2020 Oct 30.

本文引用的文献

1
Opioid agonist treatment and the process of injection drug use initiation.阿片类激动剂治疗与注射吸毒起始的过程。
Drug Alcohol Depend. 2019 Apr 1;197:354-360. doi: 10.1016/j.drugalcdep.2018.12.018. Epub 2019 Jan 22.
2
Context and characteristics of illicit drug use in coastal and interior Tanzania.坦桑尼亚沿海和内陆地区非法药物使用的背景和特点。
Int J Drug Policy. 2018 Jan;51:20-26. doi: 10.1016/j.drugpo.2017.09.012. Epub 2017 Nov 16.
3
Preventing Injection Drug use Initiation: State of the Evidence and Opportunities for the Future.预防注射吸毒的起始:证据现状与未来机遇
J Urban Health. 2018 Feb;95(1):91-98. doi: 10.1007/s11524-017-0192-8.
4
An ethnographic exploration of drug markets in Kisumu, Kenya.对肯尼亚基苏木毒品市场的人种志探索。
Int J Drug Policy. 2016 Apr;30:82-90. doi: 10.1016/j.drugpo.2016.01.001. Epub 2016 Jan 8.
5
A qualitative study of methamphetamine initiation in Cape Town, South Africa.南非开普敦甲基苯丙胺起始使用情况的定性研究。
Int J Drug Policy. 2016 Apr;30:99-106. doi: 10.1016/j.drugpo.2015.10.006. Epub 2015 Oct 28.
6
Heroin shortage in Coastal Kenya: A rapid assessment and qualitative analysis of heroin users' experiences.肯尼亚沿海地区海洛因短缺:对海洛因使用者经历的快速评估与定性分析
Int J Drug Policy. 2016 Apr;30:91-8. doi: 10.1016/j.drugpo.2015.08.010. Epub 2015 Aug 22.
7
Sexual HIV risk among substance-using female commercial sex workers in Durban, South Africa.南非德班吸毒的女性商业性工作者感染艾滋病毒的性风险。
Afr J AIDS Res. 2015;14(2):153-8. doi: 10.2989/16085906.2015.1040811.
8
Inkwari: an emerging high-risk place potentiating hiv spread among young adults in a hyper-endemic South African setting.因夸里:在南非艾滋病高发地区,一个促使艾滋病毒在年轻人中传播的新兴高风险地区。
Arch Sex Behav. 2015 Feb;44(2):307-15. doi: 10.1007/s10508-014-0330-2. Epub 2014 Aug 5.
9
Whoonga and the abuse and diversion of antiretrovirals in Soweto, South Africa.南非索韦托的“威刚”和抗逆转录病毒药物的滥用与转移。
AIDS Behav. 2014 Jul;18(7):1378-80. doi: 10.1007/s10461-013-0683-x.
10
Whoonga: potential recreational use of HIV antiretroviral medication in South Africa.南非:潜在的 HIV 抗逆转录病毒药物的娱乐性使用
AIDS Behav. 2014 Mar;18(3):511-8. doi: 10.1007/s10461-013-0575-0.