Department of Pulmonology, Kameda Medical Center, Japan.
Intern Med. 2020 Sep 15;59(18):2291-2295. doi: 10.2169/internalmedicine.4624-20. Epub 2020 Jun 15.
Sarcoidosis is a multisystem granulomatous disease of unknown etiology and is pathologically characterized by non-caseating granulomas in the organs involved. We herein report a case of sarcoidosis in a Japanese woman with acute respiratory failure, diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) on the ventilator after intubation. Only a few cases of previously undiagnosed sarcoidosis presenting acute respiratory failure have been reported. It is important to be aware that undiagnosed sarcoidosis may present with acute respiratory failure. Therefore, EBUS-TBNA under mechanical ventilation may be useful for the immediate diagnosis of patients.
结节病是一种病因不明的多系统肉芽肿性疾病，其病理特征为受累器官内无干酪样坏死性肉芽肿。本文报道了一例日本女性结节病病例，该患者因急性呼吸衰竭行气管插管，于呼吸机上接受经支气管超声引导针吸活检（EBUS-TBNA）后确诊。此前仅有少数既往未确诊的结节病导致急性呼吸衰竭的病例报道。需要注意的是，未确诊的结节病也可能表现为急性呼吸衰竭。因此，机械通气下行 EBUS-TBNA 可能有助于患者的即时诊断。
