Passoni Niccolo Maria, Peters Craig Andrew
University of Texas Southwestern Medical Center, Dallas, TX, United States.
Front Pediatr. 2020 May 27;8:242. doi: 10.3389/fped.2020.00242. eCollection 2020.
In the last decade, management of congenital UPJ obstruction has become progressively observational despite the lack of precise predictors of outcome. While it is clear that many children will have resolution of their hydronephrosis and healthy kidneys, it is equally clear that there are those in whom renal functional development is at risk. Surgical intervention for the young infant, under 6 months, has become relatively infrequent, yet can be necessary and poses unique challenges. This review will address the clinical evaluation of UPJO in the very young infant and approaches to determining in whom surgical intervention may be preferable, as well as surgical considerations for the small infant. There are some clinical scenarios where the need for intervention is readily apparent, such as the solitary kidney or in child with infection. In others, a careful evaluation and discussion with the family must be undertaken to identify the most appropriate course of care. Further, while minimally invasive pyeloplasty has become commonly performed, it is often withheld from those under 6 months. This review will discuss the key elements of that practice and offer a perspective of where minimally invasive pyeloplasty is of value in the small infant. The modern pediatric urologist must be aware of the various possible clinical situations that may be present with UPJO and feel comfortable in their decision-making and surgical care. Simply delaying an intervention until a child is bigger may not always be the best approach.
在过去十年中,尽管缺乏精确的预后预测指标,但先天性肾盂输尿管连接部梗阻(UPJ梗阻)的管理已逐渐倾向于观察性管理。虽然很明显许多儿童的肾积水会消退且肾脏健康,但同样明显的是,仍有一些儿童的肾功能发育面临风险。对于6个月以下的小婴儿,手术干预相对较少,但可能是必要的,且存在独特的挑战。本综述将探讨小婴儿UPJO的临床评估、确定哪些患儿可能更适合手术干预的方法以及小婴儿的手术注意事项。在一些临床情况下,干预的必要性显而易见,比如单肾患儿或伴有感染的患儿。在其他情况下,则必须与患儿家属进行仔细评估和讨论,以确定最合适的治疗方案。此外,虽然微创肾盂成形术已普遍开展,但通常不用于6个月以下的婴儿。本综述将讨论这种做法的关键要点,并就微创肾盂成形术在小婴儿中的价值提供一种观点。现代小儿泌尿科医生必须了解UPJO可能出现的各种临床情况,并在决策和手术治疗方面感到得心应手。仅仅将干预推迟到孩子长大可能并不总是最佳方法。