Zhao Huihui, Wu Yanni, Tao Yanling, Zhou Chunlan, De Vrieze Tessa, Li Xiaojin, Chen Liling
Author Affiliations: Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, PR China (Mss Zhao, Wu, Zhou, Li and Chen), Longgang District Central Hospital of Shenzhen, Shenzhen, Guangdong, PR China (Ms Tao) and Department of Rehabilitation Sciences, KU Leuven-University of Leuven, ResearchGroup for Rehabilitation in Internal Disorders, Leuven, Belgium (Ms De Vrieze).
Cancer Nurs. 2022;45(1):70-82. doi: 10.1097/NCC.0000000000000848.
Breast cancer-related lymphedema (BCRL) has a notable impact on patients' quality of life. However, no instrument is available to assess the problems in functioning due to BCRL in China.
The aims of this study were to translate and validate a Chinese version of the Lymphedema Functioning, Disability, and Health Questionnaire for Upper Limb Lymphedema (Lymph-ICF-UL).
A process of translation and cultural adaptation was conducted based on international standards. The study included 155 patients with BCRL and 90 patients without lymphedema. Psychometric properties that were tested consisted of internal consistency, test-rest reliability, content, construct and discriminant validity.
The Cronbach's α was .92, and intraclass correlation coefficient was 0.83. Content validity was confirmed by a sufficient content validity index in item level and scale level. Exploratory factor analysis identified 5 factors accounting for 62.44% of the total variance, and confirmatory factor analysis fit indices were acceptable. Convergent validity was supported by a moderate correlation with the 36-item Short-Form Health Survey Questionnaire and relatively weak correlations with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30. There was good divergent validity with all hypotheses evaluating divergent validity were confirmed. Significant differences were found between the lymphedema and nonlymphedema groups.
The Chinese version of the Lymph-ICF-UL is a valid and reliable instrument that can be used in both clinical and scientific settings in China.
The Chinese version of the Lymph-ICF-UL could be applicable in assessing the impairments in function, activity limitations, and participation restrictions of Chinese patients with BCRL.
乳腺癌相关淋巴水肿（BCRL）对患者的生活质量有显著影响。然而，在中国尚无用于评估BCRL所致功能问题的工具。
本研究旨在翻译并验证上肢淋巴水肿的淋巴水肿功能、残疾和健康问卷（Lymph-ICF-UL）中文版。
基于国际标准进行翻译和文化调适过程。该研究纳入了155例BCRL患者和90例无淋巴水肿患者。所测试的心理测量学特性包括内部一致性、重测信度、内容效度、结构效度和区分效度。
克朗巴哈α系数为0.92，组内相关系数为0.83。通过项目水平和量表水平上足够的内容效度指数确认了内容效度。探索性因子分析确定了5个因子，占总方差的62.44%，验证性因子分析拟合指数可接受。与36项简短健康调查问卷的中度相关性以及与欧洲癌症研究与治疗组织生活质量问卷核心30的相对较弱相关性支持了收敛效度。所有评估区分效度的假设均得到证实，具有良好的区分效度。在淋巴水肿组和非淋巴水肿组之间发现了显著差异。
Lymph-ICF-UL中文版是一种有效且可靠的工具，可在中国的临床和科研环境中使用。
Lymph-ICF-UL中文版可用于评估中国BCRL患者的功能损伤、活动受限和参与限制。
